[HTML][HTML] Thyroid hormones: possible roles in epilepsy pathology

SMS Tamijani, B Karimi, E Amini, M Golpich, L Dargahi… - Seizure, 2015 - Elsevier
Thyroid hormones (THs) l-thyroxine and l-triiodothyronine, primarily known as metabolism
regulators, are tyrosine-derived hormones produced by the thyroid gland. They play an …

Thyroid hormones and the central nervous system of mammals

I Di Liegro - Molecular medicine reports, 2008 - spandidos-publications.com
The thyroid hormones (THs) L-thyroxine (T4) and L-triiodothyronine (T3) have a profound
influence on the development and maturation of the mammalian brain, both before and after …

The role of thyroid hormone in neuronal protection

YY Liu, GA Brent - Comprehensive Physiology, 2011 - Wiley Online Library
Thyroid hormone is essential for brain development and brain function in the adult. During
development, thyroid hormone acts in a spatial and temporal‐specific manner to regulate …

A mutant thyroid hormone receptor alpha1 alters hippocampal circuitry and reduces seizure susceptibility in mice

S Hadjab-Lallemend, K Wallis, M van Hogerlinden… - …, 2010 - Elsevier
Thyroid hormone deficiency during early developmental stages causes a multitude of
functional and morphological deficits in the brain. In the present study we investigate the …

Hypothyroidism and cognitive disorders during development and adulthood: implications in the central nervous system

P Salazar, P Cisternas, M Martinez… - Molecular …, 2019 - Springer
Thyroid hormones (THs) play a critical function in fundamental signaling of the body
regulating process such as metabolism of glucose and lipids, cell maturation and …

Antiseizure medications and thyroid hormone homeostasis: literature review and practical recommendations

AM Rochtus, D Herijgers, K Jansen, B Decallonne - Epilepsia, 2022 - Wiley Online Library
Thyroid hormones play an essential role in central nervous system development, normal
physiological brain function, and repair mechanisms. On one hand, thyroid hormone …

Neuronal effects of thyroid hormone metabolites

EK Wirth, F Meyer - Molecular and Cellular Endocrinology, 2017 - Elsevier
Thyroid hormones and their metabolites are active regulators of gene expression,
mitochondrial function and various other physiological actions in different organs and …

[HTML][HTML] Effects of antiepileptic drug on thyroid hormones in patients with epilepsy: a meta-analysis

YX Zhang, CH Shen, QL Lai, GL Fang, WJ Ming, RY Lu… - Seizure, 2016 - Elsevier
Abstract Purpose As antiepileptic drugs (AEDs) are known to be associated with alterations
in thyroid profiles, we aimed to carry out a meta-analysis to comprehensively assess the …

Thyroid hormone in the CNS: contribution of neuron–glia interaction

M Noda - Vitamins and hormones, 2018 - Elsevier
The endocrine system and the central nervous system (CNS) are intimately linked. Among
hormones closely related to the nervous system, thyroid hormones (THs) are critical for the …

In quest of thyroid hormone function in mature mammalian brain

PK Sarkar - 2002 - nopr.niscpr.res.in
Thyroid hormones (TH) have important functions in maturation, differentiation and
metabolism during developmental periods in almost all types of tissues including brain of …