The adult human testis secretes a number of steroids which have potential or actual
biological activity. These substances include testosterone, 17a-hydroxyprogesterone …

A decrease in sexual activity with increasing age has been generally accepted as an
established fact by the lay public, and ever since Brown Sequard's and Voronoff's …

The development of prostatic hyperplasia is an almost universal feature of aging men and
dogs, and in both species the condition is a major cause of morbidity. Since prostatic …

The levels of steroids in prostatic tissues were determined by radioimmunoassay after
solvent extraction of a single (300–600 mg wet tissue) sample and chromatography of …

Introduction The present investigation originated in a scheme of work on the therapeutic
value of androgens in prostatic hypertrophy, undertaken under the auspices of the …

Abstract Development of prostatic hyperplasia is an almost universal feature of the aging
man and dog, and in both species the process develops only in males with intact testes. As …

In men estrogen may originate from direct glandular secretion, ie, testes or adrenal cortex,
and from the aromatization of plasma C-19 steroid precursors, eg, androstenedione and …

Testicular endocrine function and androgen-dependent secondary sexual characteristics
were assessed in 283 men 18 to 96 years of age. Mean serum total testosterone levels …

Extensive biologic and clinical investigations of the process of aging have demonstrated a
general decrease in testicular activity with increasing age. With the recent elaboration of …

There is much to suggest that testicular androgens are concerned with benign and
malignant prostatic growth. Thus, castration (presumably through removal of testicular …