Matrine inhibits the adhesion and migration of BCG823 gastric cancer cells by affecting the structure and function of the vasodilator-stimulated phosphoprotein (VASP)

J Zhang, K Su, W Shi, Y Wang, P Hu, Y Wang… - Acta Pharmacologica …, 2013 - nature.com
Aim: Vasodilator-stimulated phosphoprotein (VASP) expression is upregulated in human
cancers and correlates with more invasive advanced tumor stages. The aim of this study was …

Vasodilator-stimulated phosphoprotein regulates osteosarcoma cell migration

G Wu, L Wei, A Yu, M Zhang, B Qi, K Su… - Oncology …, 2011 - spandidos-publications.com
Vasodilator-stimulated phosphoprotein (VASP) has been reported to play an important role
in the process of cell migration and tumor metastasis. However, to date, no study has …

Vasodilator-Stimulated Phosphoprotein (VASP) depletion from breast cancer MDA-MB-231 cells inhibits tumor spheroid invasion through downregulation of Migfilin, β …

V Gkretsi, A Stylianou, T Stylianopoulos - Experimental Cell Research, 2017 - Elsevier
A hallmark of cancer cells is their ability to invade surrounding tissues and form metastases.
Cell-extracellular matrix (ECM)-adhesion proteins are crucial in metastasis, connecting …

Effect of matrine on HeLa cell adhesion and migration

L Zhang, T Wang, X Wen, Y Wei, X Peng, H Li… - European journal of …, 2007 - Elsevier
This study sought to explore the role of matrine in the metastasis of cancer cells and to gain
insight into the possible mechanism of matrine's ability to inhibit cancer metastasis …

Serine phosphorylation of vasodilator-stimulated phosphoprotein (VASP) regulates colon cancer cell survival and apoptosis

M Ali, LK Rogers, GM Pitari - Life sciences, 2015 - Elsevier
Aims In colon cancer, disease recurrence and death are associated with abnormal tumor
cell survival. Vasodilator-stimulated phosphoprotein (VASP) is an actin binding protein …

Matrine suppresses proliferation and invasion of SGC7901 cells through inactivation of PI3K/Akt/uPA pathway

X Peng, D Zhou, X Wang, Z Hu, Y Yan… - Annals of Clinical & …, 2016 - Assoc Clin Scientists
This study was to examine the inhibitory effect of matrine on the proliferation and metastasis
of gastric cancer cells, and to explore the possible mechanisms involved in these processes …

[HTML][HTML] Phosphorylated vasodilator-stimulated phosphoprotein is localized on mitotic spindles of the gastric cancer cell line SGC-7901

Y Tao, YC Chen, Y Wang, ZJ Zhang… - World Journal of …, 2006 - ncbi.nlm.nih.gov
AIM: To elucidate the localization of vasodilator stimulated phosphoprotein (VASP), a
cytoskeletal organizing protein and a substrate of protein kinases A and G in mitotic gastric …

Effect of matrine injections on invasion and metastasis of gastric carcinoma SGC-7901 cells in vitro

ZJ Dai, J Gao, WY Wu, XJ Wang, ZF Li… - Zhong yao cai …, 2007 - europepmc.org
Objective To investigate the effect of matrine injections on invasion and metastasis of gastric
carcinoma SGC-7901 cells in vitro. Methods MTT assay was used to examine the effect of …

Recent research progress of anti-tumor mechnism matrine

MJ Zhang, J Huang - Zhongguo Zhong yao za zhi= Zhongguo …, 2004 - europepmc.org
Matrine, as an active component of Chinese traditional medicine, has a great effect on anti-
inflammation, anti-arrhythmia and anti-fibrosis of liver cell. But the recent evidences indicate …

The Role of Matrine and Mitogen-Ativated Protein Kinase/Extracellular Signal-Regulated Kinase Signal Transduction in the Inhibition of the Proliferation and Migration …

LU Jinchang, LUO Qiang, P Cheng… - Chinese Journal of …, 2009 - search.ebscohost.com
Background and objective Matrine, one of the major alkaloid components of the traditional
Chinese medicine Sophora roots, has a wide range of pharmacological effects including anti …