[HTML][HTML] Comparison of PAC and MOAH for understanding the carcinogenic and developmental toxicity potential of mineral oils

JC Carrillo, L Kamelia, J Romanuka, O Kral… - Regulatory Toxicology …, 2022 - Elsevier
The carcinogenicity and developmental toxicity of unrefined mineral oil is related to its 3–7
ring polycyclic aromatic compounds (PAC) content. Therefore, refining operations focus on …

The selective determination of potentially carcinogenic polycyclic aromatic compounds in lubricant base oils by the DMSO extraction method IP346 and its correlation …

JC Carrillo, A van der Wiel, D Danneels, O Kral… - Regulatory Toxicology …, 2019 - Elsevier
Mineral oils are produced by vacuum distillation of crude oil at temperatures from∼ 300° C
to∼ 600° C. Subsequent refining processes to eliminate the carcinogenic potential of …

Correlation of mutagenic and dermal carcinogenic activities of mineral oils with polycyclic aromatic compound content

TA Roy, SW Johnson, GR Blackburn… - Fundamental and Applied …, 1988 - Elsevier
Mutagenicity, polynuclear aromatic compound content, and skin carcinogenicity were
compared for a series of complex oil mixtures derived from the refining and processing of …

Combination of multidimensional instrumental analysis and the Ames Test for the toxicological evaluation of mineral oil aromatic hydrocarbons

A Hochegger, R Wagenhofer, S Savic… - Journal of Agricultural …, 2022 - ACS Publications
Mineral oil aromatic hydrocarbons (MOAHs) include mutagenic and carcinogenic
substances and are considered a potential health risk. Current methods address the total …

Relevance of animal studies in the toxicological assessment of oil and wax hydrocarbons. Solving the puzzle for a new outlook in risk assessment

JC Carrillo, D Danneels, J Woldhuis - Critical Reviews in …, 2021 - Taylor & Francis
Paraffin waxes and white mineral oils are distinct petroleum products separated from a
common feedstock by crystallization, where only n-alkanes, iso-and cyclo-alkanes with a …

Polycyclic aromatic hydrocarbons in mineral oil, tar, and pitch, excluding petroleum pitch

MD Kipling, HA Waldron - Preventive Medicine, 1976 - Elsevier
Polycyclic aromatic hydrocarbons (PAH) occur naturally in coal and petroleum and, in
smaller amounts, in some fossilized woods, peat and lignite. Pitch, tar, and soot also contain …

Petroleum mineral oil refining and evaluation of cancer hazard

CR Mackerer, LC Griffis, JS Grabowski Jr… - Applied occupational …, 2003 - Taylor & Francis
Petroleum base oils (petroleum mineral oils) are manufactured from crude oils by vacuum
distillation to produce several distillates and a residual oil that are then further refined …

Update of the risk assessment of mineral oil hydrocarbons in food

EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2023 - Wiley Online Library
Mineral oil hydrocarbons (MOH) are composed of saturated hydrocarbons (MOSH) and
aromatic hydrocarbons (MOAH). Due to the complexity of the MOH composition, their …

Mineral oil in food, cosmetic products, and in products regulated by other legislations

R Pirow, A Blume, N Hellwig, M Herzler… - Critical reviews in …, 2019 - Taylor & Francis
For a few years, mineral oils and their potential adverse health effects have been a constant
issue of concern in many regulatory areas such as food, cosmetics, other consumer …

The mammalian toxicological hazards of petroleum-derived substances: An overview of the petroleum industry response to the high production volume challenge …

RH McKee, R White - International journal of toxicology, 2014 - journals.sagepub.com
Petroleum-derived substances are complex and composed of aliphatic (normal-, iso-, and
cycloparaffins), olefinic, and/or aromatic constituents. Approximately 400 of these complex …