Although a substantial number of randomized clinical trials (RCTs) with a radiotherapy
component have been conducted over time, it turns out that many of the trials have serious …

Purpose Randomized clinical trials (RCTs) are essential to evidence-based medicine, yet a
significant proportion fail to be completed. In radiation oncology, factors contributing to trial …

Like high-risk industries, radiotherapy requires intense attention to detail, alertness,
precision, and adequate human and material resources to minimise the risk of irreversible …

ContextThe superiority of innovative over standard treatments is not known. To describe
accurately the outcomes of innovations that are tested in randomized controlled trials (RCTs) …

Clinical trials have been the center of progress in modern medicine. In oncology, we are
fortunate to have a structure in place through the National Clinical Trials Network (NCTN) …

Radiotherapy treatment planning studies significantly contribute to advances and
improvements in radiation treatment of cancer patients. They are a pivotal step to support …

Radiotherapy utilization rates for cancer vary widely internationally. It has previously been
suggested that approximately 50% of all cancer patients should receive radiation. However …

Abstract Background Randomized controlled trials (RCTs) improve clinical care through
evidence-based results. Guidelines exist for RCT result reporting, but specific details of …

Radiation therapy is a core modality of cancer treatment; however, concerns have been
expressed regarding its underutilization and its lack of prioritization as a research domain …

A workshop entitled “Lessons Learned from Radiation Oncology Trials” was held on
December 7–8, 2011, in Bethesda, MD, to present and discuss some of the recently …