Increasing lipidomic coverage by selecting optimal mobile-phase modifiers in LC–MS of blood plasma
Reversed-phase ultrahigh-performance liquid chromatography–mass spectrometry (UHPLC–
MS) is the method of choice for lipidomic profiling of blood plasma. For comprehensive …
MS) is the method of choice for lipidomic profiling of blood plasma. For comprehensive …
Improving negative liquid chromatography/electrospray ionization mass spectrometry lipidomic analysis of human plasma using acetic acid as a mobile‐phase …
C Monnin, P Ramrup, C Daigle‐Young… - … in Mass Spectrometry, 2018 - Wiley Online Library
Rationale Mobile‐phase additives in liquid chromatography/mass spectrometry (LC/MS) are
used to improve peak shape, analyte ionization efficiency and method coverage. Both basic …
used to improve peak shape, analyte ionization efficiency and method coverage. Both basic …
[HTML][HTML] Exploiting the formation of adducts in mobile phases with ammonium fluoride for the enhancement of annotation in liquid chromatography-high resolution …
Abstract Liquid Chromatography-High Resolution Mass Spectrometry (LC-HRMS) based
lipidomics has become the most versatile analytical tool to discover and detect lipids using a …
lipidomics has become the most versatile analytical tool to discover and detect lipids using a …
Comprehensive blood plasma lipidomics by liquid chromatography/quadrupole time-of-flight mass spectrometry
K Sandra, A dos Santos Pereira… - … of chromatography A, 2010 - Elsevier
A lipidomics strategy, combining high resolution reversed-phase liquid chromatography
(RPLC) with high resolution quadrupole time-of-flight mass spectrometry (QqTOF), is …
(RPLC) with high resolution quadrupole time-of-flight mass spectrometry (QqTOF), is …
Objective set of criteria for optimization of sample preparation procedures for ultra-high throughput untargeted blood plasma lipid profiling by ultra performance liquid …
Exploratory or untargeted ultra performance liquid chromatography–mass spectrometry
(UPLC–MS) profiling offers an overview of the complex lipid species diversity present in …
(UPLC–MS) profiling offers an overview of the complex lipid species diversity present in …
Selection of internal standards for accurate quantification of complex lipid species in biological extracts by electrospray ionization mass spectrometry—What, how and …
Lipidomics is rapidly expanding because of the great facilitation of recent advances in, and
novel applications of, electrospray ionization mass spectrometry techniques. The greatest …
novel applications of, electrospray ionization mass spectrometry techniques. The greatest …
Validating quantitative untargeted lipidomics across nine liquid chromatography–high-resolution mass spectrometry platforms
Liquid chromatography–mass spectrometry (LC–MS) methods are most often used for
untargeted metabolomics and lipidomics. However, methods have not been standardized as …
untargeted metabolomics and lipidomics. However, methods have not been standardized as …
Rational selection of reverse phase columns for high throughput LC–MS lipidomics
A Criscuolo, M Zeller, K Cook, G Angelidou… - Chemistry and physics …, 2019 - Elsevier
Natural lipidomes are characterized by extremely high complexity and dynamic range of
lipid concentrations. Furthermore, high diversity of lipid physicochemical properties requires …
lipid concentrations. Furthermore, high diversity of lipid physicochemical properties requires …
Nontargeted quantitation of lipid classes using hydrophilic interaction liquid chromatography–electrospray ionization mass spectrometry with single internal standard …
E Cífková, M Holčapek, M Lísa… - Analytical …, 2012 - ACS Publications
The identification and quantitation of a wide range of lipids in complex biological samples is
an essential requirement for the lipidomic studies. High-performance liquid chromatography …
an essential requirement for the lipidomic studies. High-performance liquid chromatography …
Applications of mass spectrometry-based targeted and non-targeted lipidomics
HC Lee, T Yokomizo - Biochemical and biophysical research …, 2018 - Elsevier
Recent advances in mass spectrometry have expanded our knowledge of lipids and lipid
metabolic pathways involved in many (patho) physiological events. Targeted and non …
metabolic pathways involved in many (patho) physiological events. Targeted and non …