Effects of N-acetylprocainamide and sotalol on ion currents in isolated guinea-pig ventricular myocytes

K Komeichi, N Tohse, H Nakaya, M Shimizu… - European journal of …, 1990 - Elsevier
The effects of N-acetylprocainamide (NAPA) and sotalol on membrane current systems of
guinea-pig ventricular myocytes were examined and compared with those of quinidine using …

Effects of Quinine and Quinidine on the Transient Outward and on the L-Type Ca2+ Current in Rat Ventricular Cardiomyocytes

D Michel, JW Wegener, H Nawrath - Pharmacology, 2002 - karger.com
The effects of the enantiomers quinine and quinidine on the transient outward current (Ito)
and on the L-type Ca2+ current (ICa) were investigated in rat ventricular cardiomyocytes …

Effects of quinidine on action potentials and ionic currents in isolated canine ventricular myocytes.

JJ Salata, JA Wasserstrom - Circulation research, 1988 - Am Heart Assoc
We examined the effects of quinidine (5-20 microM) on transmembrane action potentials
and ionic currents of isolated canine ventricular myocytes. Collagenase treatment of canine …

Actions of pinacidil on membrane currents in canine ventricular myocytes and their modulation by intracellular ATP and cAMP

GN Tseng, BF Hoffman - Pflügers Archiv, 1990 - Springer
We studied the effects of pinacidil (3–50 μM) on the membrane currents of canine ventricular
myocytes, using the whole-cell variant of the patch-clamp technique, and the modulation of …

Effect of ambasilide, a new class III agent, on plateau currents in isolated guinea pig ventricular myocytes: block of delayed outward potassium current.

ZH Zhang, CH Follmer, JS Sarma… - The Journal of …, 1992 - jpet.aspetjournals.org
The actions of ambasilide (LU-47110) on the action potential and membrane currents of
isolated guinea pig ventricular myocytes were studied using voltage clamp techniques …

Blockade of 2, 4-dinitrophenol induced ATP sensitive potassium current in guinea pig ventricular myocytes by class I antiarrhythmic drugs

B Wu, T Sato, T Kiyosue, M Arita - Cardiovascular research, 1992 - academic.oup.com
Objective: The aim was to assess the effects of various antiarrhythmic drugs on 2, 4-
dinitrophenol (DNP) induced outward current (IDNP), presumably the ATP sensitive K+ …

The effect of oximes on the dihydropyridine-sensitive Ca current of isolated guinea-pig ventricular myocytes

RA Chapman - Pflügers Archiv, 1993 - Springer
Exposure of isolated guinea-pig ventricular myocytes to the uncharged oximes 2, 3
butanedionemonoxine (BDM) and norPAM (but not by the charged PAM) results in a dose …

Dual effects of dihydropyridines on whole cell and unitary calcium currents in single ventricular cells of guinea‐pig.

AM Brown, DL Kunze, A Yatani - The Journal of physiology, 1986 - Wiley Online Library
We studied the effects of dihydropyridine Ca channel ligands (DHPs), mainly nitrendipine
and Bay K8644, on whole cell and single channel Ca currents on single myocytes isolated …

[PDF][PDF] Actions of phencyclidine on the action potential and membrane currents of single guinea-pig myocytes.

RW Hadley, JR Hume - Journal of Pharmacology and Experimental …, 1986 - Citeseer
The direct actions of phencyclidine (PCP) on mammalian sarco lemma were examined by
determination of the drug's effects on the action potentials of isolated guinea-pig ventricular …

Effect of disopyramide on potassium currents in rabbit ventricular myocytes

L Virág, A Varró, JG Papp - Naunyn-Schmiedeberg's archives of …, 1998 - Springer
Abstract The effects of disopyramide (1–30 μM) on the 4-aminopyridine sensitive transient
outward current (I to), on the rapid component of the delayed rectifier potassium current (I Kr) …