[HTML][HTML] SEPT12-microtubule complexes are required for sperm head and tail formation
PL Kuo, HS Chiang, YY Wang, YC Kuo… - International journal of …, 2013 - mdpi.com
The septin gene belongs to a highly conserved family of polymerizing GTP-binding
cytoskeletal proteins. SEPTs perform cytoskeletal remodeling, cell polarity, mitosis, and …
cytoskeletal proteins. SEPTs perform cytoskeletal remodeling, cell polarity, mitosis, and …
CDC42 negatively regulates testis-specific SEPT12 polymerization
Septin (SEPT) genes encode well-preserved polymerizing GTP-binding cytoskeletal
proteins. The cellular functions of SEPTs consist of mitosis, cytoskeletal remodeling, cell …
proteins. The cellular functions of SEPTs consist of mitosis, cytoskeletal remodeling, cell …
The role of the septin family in spermiogenesis
YH Lin, YC Kuo, HS Chiang, PL Kuo - Spermatogenesis, 2011 - Taylor & Francis
Septins (full name: Septin; symbol name: SEPT) belong to a family of polymerizing GTP
binding proteins that are required for many cellular functions, including membrane …
binding proteins that are required for many cellular functions, including membrane …
Cortical organization by the septin cytoskeleton is essential for structural and mechanical integrity of mammalian spermatozoa
M Ihara, A Kinoshita, S Yamada, H Tanaka… - Developmental cell, 2005 - cell.com
Septins are polymerizing GTP binding proteins required for cortical organization during
cytokinesis and other cellular processes. A mammalian septin gene Sept4 is expressed …
cytokinesis and other cellular processes. A mammalian septin gene Sept4 is expressed …
Regulation of septin phosphorylation: SEPT12 phosphorylation in sperm septin assembly
The sperm annulus, a septin‐based ring structure, is important for reproductive physiology. It
is composed of SEPT12‐based septin core complex followed by assembling as octameric …
is composed of SEPT12‐based septin core complex followed by assembling as octameric …
SEPT12 phosphorylation results in loss of the septin ring/sperm annulus, defective sperm motility and poor male fertility
Septins are critical for numerous cellular processes through the formation of heteromeric
filaments and rings indicating the importance of structural regulators in septin assembly …
filaments and rings indicating the importance of structural regulators in septin assembly …
Sept12 is a component of the mammalian sperm tail annulus
JD Steels, MP Estey, CD Froese… - Cell motility and the …, 2007 - Wiley Online Library
Since their essential role in cytokinesis was first shown in yeast, the septins have been
described to function in diverse cellular contexts. The members of this unique class of …
described to function in diverse cellular contexts. The members of this unique class of …
ACTN4 mediates SEPT14 mutation-induced sperm head defects
Septins (SEPTs) are highly conserved GTP-binding proteins and the fourth component of the
cytoskeleton. Polymerized SEPTs participate in the modulation of various cellular processes …
cytoskeleton. Polymerized SEPTs participate in the modulation of various cellular processes …
The expression level of septin12 is critical for spermiogenesis
YH Lin, YM Lin, YY Wang, IS Yu, YW Lin… - The American journal of …, 2009 - Elsevier
Septins belong to a family of polymerizing GTP-binding proteins that are required for many
cellular functions, such as membrane compartmentalization, vesicular trafficking, mitosis …
cellular functions, such as membrane compartmentalization, vesicular trafficking, mitosis …
SEPT12 orchestrates the formation of mammalian sperm annulus by organizing core octameric complexes with other SEPT proteins
YC Kuo, YR Shen, HI Chen, YH Lin… - Journal of cell …, 2015 - journals.biologists.com
Male infertility has become a worldwide health problem, but the etiologies of most cases are
still unknown. SEPT12, a GTP-binding protein, is involved in male fertility. Two SEPT12 …
still unknown. SEPT12, a GTP-binding protein, is involved in male fertility. Two SEPT12 …