Primary Sjögren's syndrome (pSS) is a chronic autoimmune disease characterized by
lymphocytic infiltration and tissue destruction of exocrine glands such as salivary glands …

Primary Sjögren syndrome (pSS) is a prototypical autoimmune disease. The involvement of
B cells in the pathogenesis of pSS has long been suspected on the basis of clinical …

In primary Sjögren's syndrome (pSS), FcRL4+ B cells are present in inflamed salivary gland
tissue, within or in close proximity to ductal epithelium. FcRL4 is also expressed by nearly all …

Biological abnormalities associated with B lymphocytes are a hallmark of patients with
primary Sjögren's syndrome. Those patients present abnormal distribution of B lymphocytes …

Increased numbers of T follicular helper (Tfh) cells have been implicated in the development
of autoimmune diseases including primary Sjögren's syndrome (pSS), but how the Tfh cell …

Primary Sjögren's syndrome (pSS) is a chronic autoimmune systemic disease, characterized
by a lymphoplasmocytic infiltration and a progressive destruction of salivary and lachrymal …

Primary Sjögren's syndrome (pSS) is often considered a B cell-mediated disease, yet the
precise role of B cells in the pathogenesis is not fully understood. This is exemplified by the …

Sjögren's Syndrome (SS) is a chronic inflammatory disorder affecting exocrine glands, in
particular the lacrimal and salivary glands. The disease can be primary (pSS) or secondary …

In primary Sjögren syndrome (pSS), the function of the salivary glands is often considerably
reduced. Multiple innate immune pathways are likely dysregulated in the salivary gland …

With the ability to induce T cell activation and elicit humoral responses, B cells are generally
considered as effectors of the immune system. However, the emergence of regulatory B cells …