Synthetic peptides derived from naturally occurring host defence peptides (HDPs) have
garnered significant attention as novel pharmaceuticals, particularly as alternatives to …

There is increasing interest in developing cationic host defense peptides (HDPs) and their
synthetic derivatives as antimicrobial, immunomodulatory, and anti-biofilm agents. These …

The multifunctional properties of host defense peptides (HDPs) make them promising drug
candidates to tackle bacterial infections and tissue inflammation. However, these peptides …

Innate defense regulator-1002 (IDR-1002) is a synthetic peptide with promising
immunomodulatory and antibiofilm properties. An appreciable body of work exists around its …

With the continued rise in antibiotic-resistant bacteria, there is an immense need for the
development of new therapeutic agents. Host-defense peptides (HDPs) offer a unique …

Host defence peptides (HDPs) are multi-functional inducers and effectors of host immunity.
Through their direct antimicrobial activity HDPs have for been successfully utilized for many …

One of the most significant advances in medical history is the discovery and development of
antibiotics, which in the middle of last century was flourishing and appeared to be the …

Natural cationic host defence (antimicrobial) peptides are widely distributed gene encoded
molecules with diverse structures. There are more than 1200 natural Host Defence Peptides …

Non-natural amino acids can be incorporated into synthetic host defense peptides (HDPs) to
modulate their susceptibility to proteolytic degradation. However, the impact of non-natural …

In the last few years, the number of bacteria with enhanced resistance to conventional
antibiotics has dramatically increased. Most of such bacteria belong to regular microbial …