Combination of clinical symptoms and blood biomarkers can improve discrimination between bacterial or viral community-acquired pneumonia in children

MU Bhuiyan, CC Blyth, R West, J Lang… - BMC pulmonary …, 2019 - Springer
Background Differentiating bacterial from viral pneumonia is important for guiding targeted
management and judicious use of antibiotics. We assessed if clinical characteristics and …

Systematic review and meta-analysis of diagnostic biomarkers for pediatric pneumonia

LC Gunaratnam, JL Robinson… - Journal of the Pediatric …, 2021 - academic.oup.com
Background Pneumonia causes significant morbidity and mortality in children worldwide,
especially in resource-poor settings. Accurate identification of bacterial etiology leads to …

Development and validation of a clinical prediction rule to distinguish bacterial from viral pneumonia in children

L Moreno, JA Krishnan, P Duran… - Pediatric …, 2006 - Wiley Online Library
Background Distinguishing bacterial from viral pneumonia on admission to the hospital
could guide the decision of whether or not to use antibiotics. We developed and validated a …

Biomarkers and disease severity in children with community-acquired pneumonia

TA Florin, L Ambroggio, C Brokamp, Y Zhang… - …, 2020 - publications.aap.org
BACKGROUND: Host biomarkers predict disease severity in adults with community-
acquired pneumonia (CAP). We evaluated the association of the white blood cell (WBC) …

A three-step diagnosis of pediatric pneumonia at the emergency department using clinical predictors, C-reactive protein, and pneumococcal PCR

G Alcoba, K Keitel, V Maspoli, L Lacroix… - European journal of …, 2017 - Springer
Recommendations for the management of community-acquired pneumonia (CAP) advocate
that, in the absence of the clinical and laboratory findings typical of bacterial CAP, antibiotics …

Clinical features and inflammatory markers in pediatric pneumonia: a prospective study

AS Berg, CS Inchley, HO Fjaerli, TM Leegaard… - European journal of …, 2017 - Springer
In this prospective, observational study on previously healthy children< 18 years, we aimed
to study the diagnostic ability of clinical features and inflammatory markers to (i) predict …

Differentiation of bacterial and viral community‐acquired pneumonia in children

M Don, F Valent, M Korppi… - Pediatrics International, 2009 - Wiley Online Library
Background: Microbe‐specific diagnosis of pediatric community‐acquired pneumonia (CAP)
and the distinction between typical‐bacterial, atypical‐bacterial and viral cases are difficult …

[HTML][HTML] Utility of inflammatory markers in predicting the aetiology of pneumonia in children

MA Elemraid, SP Rushton, MF Thomas… - … and infectious disease, 2014 - Elsevier
We aimed to investigate the diagnostic value of applying cut-off levels of inflammatory
markers and to develop a prediction model for differentiation between bacterial and viral …

Blood biomarkers differentiating viral versus bacterial pneumonia aetiology: a literature review

J Thomas, A Pociute, R Kevalas, M Malinauskas… - Italian journal of …, 2020 - Springer
Background and objectives The goal of this literature review is to compare current studies
regarding the accuracy of different serum markers in differentiating viral from bacterial …

Non‐specific host response markers in the differentiation between pneumococcal and viral pneumonia: What is the most accurate combination?

M Korppi - Pediatrics international, 2004 - Wiley Online Library
Background: Serum C‐reactive protein (CRP), blood white cell count (WBC), serum
procalcitonin (PCT) and erythrocyte sedimentation rate (ESR) were measured in 132 …