The RNA interference (RNAi) mediated by homology-dependent degradation of the target
mRNA with small RNA molecules plays a key role in controlling transcription and translation …

Cosuppression is a silencing phenomenon triggered by the introduction of homologous
DNA sequences into the genomes of organisms as diverse as plants, fungi, flies, and …

Cryptococcus neoformans infections cause approximately 15% of AIDS-related deaths
owing to a combination of limited antifungal therapies and drug resistance. A collection of …

Cryptococcus neoformans is a pathogenic fungus responsible for serious disease in
immunocompromised individuals. This organism has recently been developed as an …

RNAi is a ubiquitous pathway that serves central functions throughout eukaryotes, including
maintenance of genome stability and repression of transposon expression and movement …

The increasing knowledge on the functional relevance of endogenous small RNAs
(esRNAs) as riboregulators has stimulated the identification and characterization of these …

Cryptococcus neoformans is a pathogenic basidiomycetous yeast responsible for more than
600,000 deaths each year. It occurs as two serotypes (A and D) representing two varieties …

Introduction of DNA sequences into the genome often results in homology-dependent gene
silencing in organisms as diverse as plants, fungi, flies, nematodes, and mammals. We …

RNA interference is a conserved homology-dependent post-transcriptional/transcriptional
gene silencing mechanism in eukaryotes. The filamentous fungus Neurospora crassa is one …

We recently reported transposon mutagenesis as a significant driver of spontaneous
mutations in the human fungal pathogen Cryptococcus deneoformans during murine …