Classical granulation theory recognises wetting and nucleation, consolidation and growth,
and breakage and attrition as mechanisms that contribute to the formation of granules during …

Past granulation research has been essentially restricted to a macroscopic study of the
impact of operating variables on granule morphology. While fundamental groundwork …

The mechanisms of early granule growth are difficult to study and poorly understood.
Consolidation and layering play a critical role in the growth process. However, little is known …

Further experimental investigation based on a microscopic, or single granule, scale has
been conducted to investigate the uniformity of binder composition within a given size class …

In this study, experimentation and modelling were carried out to understand the granulation
process. This work assesses whether there is a significant difference in the aggregation rate …

Granule breakage is an important rate process in wet granulation that promotes product
uniformity and controls product size and strength. In this work, a model to predict granule …

Response surface methodology was used to investigate the effects of operating parameters
such as impeller speed, binder mass and granulation time on the average size of granules …

Granulation provides a complete and comprehensive introduction on the state-of-the-art of
granulation and how it can be applied both in an academic context and from an industrial …

It is possible to link granulation rates to granule properties. The linkage is by multiple
dimension population balance equations that, by means of simplifying assumptions, can be …

Despite the volume of research concerning granulation, the knowledge of its rate behaviour
is still a matter of some debate. Here, granulation is explored by looking at the interaction …