One of the ultimate goals of biological research is to understand mechanisms of cell function
within living organisms. With this in mind, many sophisticated technologies that allow us to …

Publisher Summary The chapter focuses on the application of different ultrastructural
cytochemical methods that contributed an important way to the understanding of the …

In this review we describe major contributions of light and electron microscopic approaches
to the present understanding of functional nuclear architecture. The large gap of knowledge …

Publisher Summary This chapter provides an overview to both standard and advanced
methods for the sample preparation, staining, and structural analysis of nuclear architecture …

In addition to X-ray diffraction and NMR spectroscopy, microscopes (ie, light, electron, and
scanning probe microscopes) definitely have become an integrated part of modern structure …

The second volume of the series Manuals in Biomedical Research, this book is aimed to be
both a concise introduction to the diverse field of microscopy and a practical guide those …

Full article: Correlating Light and Electron Microscopy Skip to Main Content Taylor and Francis
Online homepage Taylor and Francis Online homepage Log in | Register Cart 1.Home 2.All …

Highlights•Biophysical methods for studying proteins in situ reached unprecedented levels
of maturity.•Direct investigations of cellular protein structures and functions are now …

Light and electron microscopy each have certain advantages and limitations for the
investigation of the cytoskeleton. Light microscopy, especially with recent progress in …

Immobilized proteins within the nucleus are usually identified by treating cells with
detergent. The detergent-resistant fraction is often assumed to be chromatin and is …