Approaches to develop alternative testing strategies to inform human health risk assessment of nanomaterials

V Stone, HJ Johnston, D Balharry, JM Gernand… - Risk …, 2016 - Wiley Online Library
The development of alternative testing strategies (ATS) for hazard assessment of new and
emerging materials is high on the agenda of scientists, funders, and regulators. The …

Human Health Risks of Engineered Nanomaterials: Critical Knowledge Gaps in Nanomaterials Risk Assessment

A Elder, I Lynch, K Grieger, S Chan-Remillard… - Nanomaterials: risks and …, 2009 - Springer
There are currently hundreds of available consumer products that contain nanoscale
materials. Human exposure is, therefore, likely to occur in occupational and environmental …

Principles for characterizing the potential human health effects from exposure to nanomaterials: elements of a screening strategy

G Oberdörster, A Maynard, K Donaldson… - Particle and fibre …, 2005 - Springer
The rapid proliferation of many different engineered nanomaterials (defined as materials
designed and produced to have structural features with at least one dimension of 100 …

Moving toward exposure and risk evaluation of nanomaterials: challenges and future directions

T Thomas, T Bahadori, N Savage… - Wiley Interdisciplinary …, 2009 - Wiley Online Library
Nanotechnology, the commercial development of engineered nanomaterials, promises
breakthrough innovations by enhancing the performance of existing consumer products and …

[HTML][HTML] Comparative assessment of nanomaterial definitions and safety evaluation considerations

DR Boverhof, CM Bramante, JH Butala… - Regulatory Toxicology …, 2015 - Elsevier
Nanomaterials continue to bring promising advances to science and technology. In concert
have come calls for increased regulatory oversight to ensure their appropriate identification …

Development of a preliminary framework for informing the risk analysis and risk management of nanoparticles

K Morgan - Risk Analysis: An International Journal, 2005 - Wiley Online Library
Erratum Risk Analysis 25: 3, 711‐718 Decisions are often made even when there is
uncertainty about the possible outcomes. However, methods for making decisions with …

Risk assessment approaches and research needs for nanomaterials: an examination of data and information from current studies

E Kuempel, C Geraci, P Schulte - Nanotechnol Toxicol Iss Environ Saf, 2007 - Springer
Risk assessment is an important component in the development of effective risk
management strategies. Toxicology, epidemiology, and workplace comparison to new …

Framework to Evaluate Exposure Relevance and Data Needs for Risk Assessment of Nanomaterials using in Vitro Testing Strategies

M Sharma, JA Shatkin, C Cairns, R Canady… - Risk …, 2016 - Wiley Online Library
This article presents a multistage framework for evaluating the strength of evidence of
nanomaterial (NM) exposure characterization data to optimize the utility of in vitro testing …

[HTML][HTML] Methods and data for regulatory risk assessment of nanomaterials: Questions for an expert consultation

PG Sayre, KG Steinhäuser, T van Teunenbroek - NanoImpact, 2017 - Elsevier
While the general risk assessment paradigm, and associated endpoints for regulatory
review and approval of conventional chemicals in essence apply to nanomaterials, two …

Advancing risk analysis for nanoscale materials: report from an international workshop on the role of alternative testing strategies for advancement

JA Shatkin, KJ Ong, C Beaudrie, AJ Clippinger… - Risk …, 2016 - Wiley Online Library
The Society for Risk Analysis (SRA) has a history of bringing thought leadership to topics of
emerging risk. In September 2014, the SRA Emerging Nanoscale Materials Specialty Group …