In eukaryotic cells, genomic DNA is highly packaged into chromatin to fit inside the nucleus.
The accessibility of DNA is dependent on the packing density of chromatin fibers, which …

Chromatin is a complex of DNA and proteins that organizes the genetic material in the
eukaryotic nucleus. The dynamics and structure of chromatin are directly involved in control …

The chromatin fiber consists of a string of nucleosomes connected by linker DNA regions.
The hierarchy of folding of this fiber within the cell has long been controversial, and the …

Chromatin structure plays a fundamental role in the regulation of nuclear processes such as
DNA transcription, replication, recombination, and repair. Despite considerable efforts …

In eukaryotes, genomic DNA is packaged into chromatin in the nucleus. The accessibility of
DNA is dependent on the chromatin structure and dynamics, which essentially control DNA …

The structure of compact 30‐nm chromatin fibres is still debated. We present here a novel
unified model that reconciles all experimental observations into a single framework. We …

In eukaryotes, genomic DNA is hierarchically packaged by histones into chromatin on
several levels to fit inside the nucleus. As a central-level structure between nucleosomal …

Eukaryotic genomes are organized hierarchically into chromatin structures by histones.
Despite extensive research for over 30 years, not only the fundamental structure of the 30 …

Higher-Order Structures of Chromatin: The Elusive 30 nm Fiber: Cell Skip to Main Content
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Genomic DNA in the eukaryotic nucleus is hierarchically packaged by histones into
chromatin to fit inside the nucleus. The dynamics of higher-order chromatin compaction play …