In the last two decades, the zebrafish has emerged as an important model species for heart
regeneration studies. Various approaches to model loss of cardiac myocytes and myocardial …

Zebrafish have the capacity to regenerate most of its organs upon injury, including the heart.
Due to its amenability for genetic manipulation, the zebrafish is an excellent model organism …

The zebrafish (Danio rerio) possesses a spectacular capacity for cardiac regeneration.
Zebrafish have been used in cardiac regeneration research for nearly two decades …

Despite current treatment regimens, heart failure still remains one of the leading causes of
morbidity and mortality in the world due to failure to adequately replace lost ventricular …

The mammalian heart is incapable of significant regeneration following an acute injury such
as myocardial infarction1. By contrast, urodele amphibians and teleost fish retain a …

The zebrafish has emerged as an important model organism for understanding the cellular
and molecular mechanisms of tissue regeneration. Adult zebrafish efficiently replace cardiac …

Heart failure caused by cardiomyocyte loss after ischemic tissue damage is a leading cause
of death worldwide. Although adult mammalian cardiomyocytes are able to proliferate during …

In mammals, myocardial cell death due to infarction results in scar formation and little
regenerative response. In contrast, zebrafish have a high capacity to regenerate the heart …

Background In humans, myocardial infarction is characterized by irreversible loss of heart
tissue, which becomes replaced with a fibrous scar. By contrast, teleost fish and urodele …

Adult zebrafish possess an elevated cardiac regenerative capacity as compared with adult
mammals. In the past two decades, zebrafish have provided a key model system for studying …