Background: There is increasing evidence suggesting the contribution of platelets in the
vaso-occlusive phenomena found in sickle cell anaemia. This study is aimed at using …

Background: The platelet count, prothrombin time (PT), activated partial thromboplastin time
(APTT) and D-dimer levels of patients with sickle cell disease (SCD) in steady state (32 …

Background: Sickle cell disease (SCD) is a hereditary haemoglobinopathy characterized by
deranged haematopoiesis, and intermittent occlusion of small blood vessels. Patients can …

Background: Sickle cell anaemia (SCA) is a major cause of morbidity and mortality in Africa
where there is no readily available effective treatment. This study was designed to determine …

Abstract Background/Aim: Painful vaso-occlusive crisis (VOC) is the most frequent
complication of sickle cell disease. The cause of VOC is believed to be ischemic tissue injury …

Objective: The purpose of this study was to determine the impact of mean platelet volume
(MPV) on the frequency and severity of vaso-occlusive and cerebrovascular events in …

One hundred patients with sickle cell anaemia (SCA) in steady state within the ages of 1-30
years were studied with respect to haematocrit and platelet count. The same number of age …

From July 1990 to January 1991 we studied platelet functions in 55 indigenous Kenyan
patients (23 males and 32 females) with sickle cell anaemia (SCA) in steady state (SCASS) …

Background: Reports from various studies showed that patients with sickle cell anemia
(SCA) have altered components of hemostasis such as platelet function, the procoagulant …

Aim: To assess the use of mean platelet volume (MPV) as a prognostic indicator of sickle cell
disease (SCD). Materials and methods: Fifty sickle cell patients aged 18 to 60 years …