Indications and options of new immune modulatory therapies for Sjögren's syndrome

E Feist, T Dörner, A Hansen - Zeitschrift fur Rheumatologie, 2007 - europepmc.org
Sjögren's syndrome is a systemic inflammatory rheumatic disorder of unknown origin with so
far inadequate therapy options. Management of Sjögren's syndrome is still primarily …

Biologic therapies in primary Sjögren's syndrome.

SJ Bowman - Current Pharmaceutical Biotechnology, 2012 - europepmc.org
Primary Sjögren's Syndrome (PSS) is characterized by dryness of the eyes and mouth due
to lymphocytic infiltration of secretory exocrine glands. As well as disabling dryness, patients …

Use of Rituximab in the Management of Sjögren's Syndrome

F Carubbi, A Alunno, P Cipriani, O Berardicurti… - … Treatment Options in …, 2015 - Springer
Opinion statement Primary Sjögren's syndrome (pSS) is an autoimmune disease, showing a
broad heterogeneity concerning the symptoms, the involved organs, as well as the …

How to assess treatment efficacy in Sjögren's syndrome?

A Vissink, H Bootsma, FGM Kroese… - Current opinion in …, 2012 - journals.lww.com
How to assess treatment efficacy in Sjögren's syndrome? : Current Opinion in Rheumatology
How to assess treatment efficacy in Sjögren's syndrome? : Current Opinion in Rheumatology …

Rituximab in the treatment of Sjögren's syndrome: is it the right or wrong drug?

H Bootsma, FGM Kroese… - Arthritis & Rheumatology, 2017 - search.ebscohost.com
The authors focus on the role of B cells in the pathogenesis of a heterogeneous disease
known as Sjögren's syndrome (SS). They discuss the effectiveness of a potent biologic …

Issues related to clinical trials of oral and biologic disease-modifying agents for Sjögren's syndrome

SE Carsons - Rheumatic Disease Clinics of North America, 2008 - Elsevier
Published studies and trials of oral and biologic disease-modifying antirheumatic drugs for
the treatment of Sjögren's syndrome have shown disappointing results. Improvements in trial …

Cytokines as therapeutic targets in primary Sjögren syndrome

S Retamozo, A Flores-Chavez… - Pharmacology & …, 2018 - Elsevier
Primary Sjögren syndrome (SjS) is a systemic autoimmune disease that may affect 1 in 1000
people (overwhelmingly women) and that can be a serious disease with excess mortality …

The uncertain role of immunosuppressive agents in Sjögren's syndrome

G Linardaki, HM Moutsopoulos - … Clinic journal of …, 1997 - pubmed.ncbi.nlm.nih.gov
Although Sjögren's syndrome is an autoimmune disorder, immunosuppressive agents have
yielded disappointing results in clinical trials. In this paper we summarize our experience …

Tolerance and efficacy of rituximab and changes in serum B cell biomarkers in patients with systemic complications of primary Sjögren's syndrome

R Seror, C Sordet, L Guillevin, E Hachulla… - Annals of the …, 2007 - ard.bmj.com
Objective: To investigate the safety and efficacy of rituximab (RTX) for systemic symptoms in
patients with primary Sjögren's syndrome (pSS), and changes in B cell biomarkers. Patients …

Biologic therapy in the treatment of Sjögren's syndrome: a clinical perspective

CR Johr, FB Vivino - Current Treatment Options in Rheumatology, 2018 - Springer
Purpose of review Sjögren's syndrome (SS) is an autoimmune disease characterized by
sicca symptoms, musculoskeletal pain, and systemic manifestations. Biologic therapies have …