Chemotopic odorant coding in a mammalian olfactory system

BA Johnson, M Leon - Journal of Comparative Neurology, 2007 - Wiley Online Library
Systematic mapping studies involving 365 odorant chemicals have shown that glomerular
responses in the rat olfactory bulb are organized spatially in patterns that are related to the …

Modular representations of odorants in the glomerular layer of the rat olfactory bulb and the effects of stimulus concentration

BA Johnson, M Leon - Journal of Comparative Neurology, 2000 - Wiley Online Library
To study the mechanism whereby odorants are encoded in the nervous system, we studied
the glomerular‐layer activity patterns in the rat olfactory bulb evoked by closely related …

Functional mapping of the rat olfactory bulb using diverse odorants reveals modular responses to functional groups and hydrocarbon structural features

BA Johnson, SL Ho, Z Xu, JS Yihan… - Journal of …, 2002 - Wiley Online Library
In an effort to understand the olfactory code of rats, we collected more than 1,500,000
measurements of glomerular activity in response to 54 odorants selected to provide …

Local and global chemotopic organization: general features of the glomerular representations of aliphatic odorants differing in carbon number

BA Johnson, H Farahbod, Z Xu… - Journal of …, 2004 - Wiley Online Library
To determine whether there is a general strategy used by the olfactory system to represent
odorants differing in carbon chain length, rats were exposed to homologous series of …

Spatial coding of odorant features in the glomerular layer of the rat olfactory bulb

BA Johnson, CC Woo, M Leon - Journal of Comparative …, 1998 - Wiley Online Library
In order to determine whether molecular features of odorants are represented spatially in the
glomerular layer of the olfactory bulb, we used metabolic mapping of [14C] 2‐deoxyglucose …

Multidimensional chemotopic responses to n‐aliphatic acid odorants in the rat olfactory bulb

BA Johnson, CC Woo, EE Hingco… - Journal of …, 1999 - Wiley Online Library
In an effort to understand the means by which similar chemical odorants are encoded in the
mammalian brain, we exposed rats to a homologous series of n‐aliphatic acids and mapped …

Peripheral odor coding in the rat and frog: quality and intensity specification

P Duchamp-Viret, A Duchamp… - Journal of …, 2000 - Soc Neuroscience
In mammals, two recent studies have shown recently that one odor molecule can be
recognized by several molecular olfactory receptors (ORs), and a single OR can recognize …

Distributed representation of chemical features and tunotopic organization of glomeruli in the mouse olfactory bulb

L Ma, Q Qiu, S Gradwohl, A Scott… - Proceedings of the …, 2012 - National Acad Sciences
In the mammalian brain, similar features of the sensory stimuli are often represented in
proximity in the sensory areas. However, how chemical features are represented in the …

Symmetry, stereotypy, and topography of odorant representations in mouse olfactory bulbs

L Belluscio, LC Katz - Journal of Neuroscience, 2001 - Soc Neuroscience
The molecular basis of vertebrate odorant representations has been derived extensively
from mice. The functional correlates of these molecular features were visualized using …

Olfactory coding in the mammalian olfactory bulb

M Leon, BA Johnson - Brain research reviews, 2003 - Elsevier
There have been a number of recent approaches to the study of olfactory coding, each of
which has its advantages and disadvantages. In the present review, we discuss our own …