Functional mapping of the rat olfactory bulb using diverse odorants reveals modular responses to functional groups and hydrocarbon structural features

BA Johnson, SL Ho, Z Xu, JS Yihan… - Journal of …, 2002 - Wiley Online Library
In an effort to understand the olfactory code of rats, we collected more than 1,500,000
measurements of glomerular activity in response to 54 odorants selected to provide …

Interactions between odorant functional group and hydrocarbon structure influence activity in glomerular response modules in the rat olfactory bulb

BA Johnson, H Farahbod… - Journal of Comparative …, 2005 - Wiley Online Library
To investigate the effect of odorant hydrocarbon structure on spatial representations in the
olfactory bulb systematically, we exposed rats to odorant chemicals possessing one of four …

Modular representations of odorants in the glomerular layer of the rat olfactory bulb and the effects of stimulus concentration

BA Johnson, M Leon - Journal of Comparative Neurology, 2000 - Wiley Online Library
To study the mechanism whereby odorants are encoded in the nervous system, we studied
the glomerular‐layer activity patterns in the rat olfactory bulb evoked by closely related …

Effects of functional group position on spatial representations of aliphatic odorants in the rat olfactory bulb

BA Johnson, H Farahbod, S Saber… - Journal of Comparative …, 2005 - Wiley Online Library
Principles of olfactory coding can be clarified by studying the olfactory bulb activity patterns
that are evoked by odorants differing systematically in chemical structure. In the present …

Spatial representations of odorants in olfactory bulbs of rats and mice: similarities and differences in chemotopic organization

BA Johnson, Z Xu, SS Ali… - Journal of Comparative …, 2009 - Wiley Online Library
In previous studies, we mapped glomerular layer 2‐deoxyglucose uptake evoked by
hundreds of both systematically related and chemically distinct odorants in rat olfactory …

Spatial coding of odorant features in the glomerular layer of the rat olfactory bulb

BA Johnson, CC Woo, M Leon - Journal of Comparative …, 1998 - Wiley Online Library
In order to determine whether molecular features of odorants are represented spatially in the
glomerular layer of the olfactory bulb, we used metabolic mapping of [14C] 2‐deoxyglucose …

Chemotopic odorant coding in a mammalian olfactory system

BA Johnson, M Leon - Journal of Comparative Neurology, 2007 - Wiley Online Library
Systematic mapping studies involving 365 odorant chemicals have shown that glomerular
responses in the rat olfactory bulb are organized spatially in patterns that are related to the …

Local and global chemotopic organization: general features of the glomerular representations of aliphatic odorants differing in carbon number

BA Johnson, H Farahbod, Z Xu… - Journal of …, 2004 - Wiley Online Library
To determine whether there is a general strategy used by the olfactory system to represent
odorants differing in carbon chain length, rats were exposed to homologous series of …

Long hydrocarbon chains serve as unique molecular features recognized by ventral glomeruli of the rat olfactory bulb

SL Ho, BA Johnson, M Leon - Journal of Comparative …, 2006 - Wiley Online Library
In an effort to understand mammalian olfactory processing, we have been describing the
responses to systematically different odorants in the glomerular layer of the main olfactory …

Spatial representation of hydrocarbon odorants in the ventrolateral zones of the rat olfactory bulb

KM Igarashi, K Mori - Journal of neurophysiology, 2005 - journals.physiology.org
The glomerular sheet of the olfactory bulb (OB) forms odorant receptor maps that are
parceled into zones. We previously reported the molecular receptive range (MRR) property …