It is estimated that 10–15% of couples are infertile and male factors account for about half of
these cases. With the advent of intracytoplasmic sperm injection (ICSI), many infertile men …

The SEPTIN12 gene has been associated with male infertility. Male Septin12+/− chimera
mice were infertile, supporting the prevailing view that SEPTIN12 haploinsufficiency causes …

The main objective of this study was to evaluate the potential genetic effects of SEPT14 on
male infertility through sequencing the SEPT14 coding region. To address this research gap …

Septins are members of the GTPase superfamily, which has been implicated in diverse
cellular functions including cytokinesis and morphogenesis. Septin 12 (SEPT12) is a testis …

Male infertility is observed in approximately 50% of all couples with infertility.
Intracytoplasmic sperm injection (ICSI), a conventional artificial reproductive technique for …

Septins belong to a family of polymerizing GTP-binding proteins that are required for many
cellular functions, such as membrane compartmentalization, vesicular trafficking, mitosis …

SEPT12 is a testis‐specific gene involved in the terminal differentiation of male germ cells.
SEPT12 protein is required for sperm head‐tail formation and acts as a fundamental …

Septins (full name: Septin; symbol name: SEPT) belong to a family of polymerizing GTP
binding proteins that are required for many cellular functions, including membrane …

Septins are critical for numerous cellular processes through the formation of heteromeric
filaments and rings indicating the importance of structural regulators in septin assembly …

Oocytes fertilized with spermatozoa obtained from Septin 12+/–chimeric mice failed to
develop beyond the morula stage after IVF and intracytoplasmic sperm injection because of …