Management of common side effects of apremilast

A Langley, J Beecker - Journal of cutaneous medicine and …, 2018 - journals.sagepub.com
Apremilast is a relatively new therapy for the treatment of moderate to severe plaque
psoriasis in adults. While this medication is considered safe with a very low risk of serious …

Four‐year drug survival of apremilast in patients with psoriasis

M Kishimoto, M Komine, K Kamiya… - The Journal of …, 2023 - Wiley Online Library
This real‐world study at a single academic center retrospectively examined the drug survival
of apremilast for patients with psoriasis. Retrospective information was extracted from the …

[HTML][HTML] Long-term safety and tolerability of apremilast in patients with psoriasis: Pooled safety analysis for≥ 156 weeks from 2 phase 3, randomized, controlled trials …

J Crowley, D Thaçi, P Joly, K Peris, KA Papp… - Journal of the american …, 2017 - Elsevier
Background Randomized, controlled trials demonstrated efficacy and safety of apremilast for
moderate-to-severe plaque psoriasis and psoriatic arthritis. Objective Assess long-term …

Apremilast as a treatment for psoriasis

B Shutty, C West, M Pellerin… - Expert Opinion on …, 2012 - Taylor & Francis
Introduction: Psoriasis is a common skin disorder characterized by chronic inflammatory
lesions that are frequently vexing for patients and difficult for physicians to treat. Although …

[HTML][HTML] Apremilast in psoriasis patients with serious comorbidities: a case series and systematic review of literature

A Tsentemeidou, E Sotiriou, N Sideris… - Dermatology Practical …, 2022 - ncbi.nlm.nih.gov
Objectives The aim of this paper is to present our personal as well as literature-sourced real-
world evidenced on apremilast use in psoriasis patients with serious baseline comorbidities …

Efficacy and safety of apremilast monotherapy for moderate to severe psoriasis: retrospective study

A Ighani, JR Georgakopoulos, LL Zhou… - Journal of …, 2018 - journals.sagepub.com
Background: Apremilast is a new oral drug for the treatment of moderate to severe plaque
psoriasis that reduces inflammation by inhibiting phosphodiesterase 4. Its efficacy and safety …

Safety evaluation of apremilast for the treatment of psoriasis

A Dattola, E Del Duca, R Saraceno… - Expert opinion on …, 2017 - Taylor & Francis
ABSTRACT Introduction: Psoriasis (PSo) is a chronic inflammatory skin disease associated
with co-morbidities such as hypertension, diabetes, dyslipidemia and metabolic syndrome. It …

Efficacy and safety of apremilast in subjects with moderate to severe plaque psoriasis: results from a phase II, multicenter, randomized, double‐blind, placebo …

KA Papp, R Kaufmann, D Thaçi, C Hu… - Journal of the …, 2013 - Wiley Online Library
Background Apremilast, a small molecule specific inhibitor of phosphodiesterase 4, works
intracellularly to modulate pro‐inflammatory and anti‐inflammatory mediator production …

Apremilast: a review in psoriasis and psoriatic arthritis

ED Deeks - Drugs, 2015 - Springer
Apremilast (Otezla®) is an oral phosphodiesterase 4 inhibitor indicated for the twice-daily
treatment of adults with psoriasis and psoriatic arthritis (PsA). Its use in these patient …

Long-term effectiveness and drug survival of apremilast in treating psoriasis: a real-world experience

J Distel, S Cazzaniga, SM Seyed Jafari, V Emelianov… - Dermatology, 2022 - karger.com
Background: Apremilast is an oral phosphodiesterase 4 (PDE4) inhibitor used for the
treatment of moderate to severe psoriasis. Long-term data on the effectiveness and drug …