Antipsychotics, other psychotropics, and the risk of death in patients with dementia: number needed to harm

DT Maust, HM Kim, LS Seyfried, C Chiang… - JAMA …, 2015 - jamanetwork.com
Importance Antipsychotic medications are associated with increased mortality in older adults
with dementia, yet their absolute effect on risk relative to no treatment or an alternative …

Risk of mortality among individual antipsychotics in patients with dementia

HC Kales, HM Kim, K Zivin… - American Journal of …, 2012 - Am Psychiatric Assoc
Objective: The use of antipsychotics to treat the behavioral symptoms of dementia is
associated with greater mortality. The authors examined the mortality risk of individual …

Short-and long-term mortality risk associated with the use of antipsychotics among 26,940 dementia outpatients: a population-based study

EM Langballe, B Engdahl, H Nordeng, C Ballard… - The American Journal of …, 2014 - Elsevier
Objective To investigate short-and long-term mortality risk associated with the use of
antipsychotics in dementia outpatients, assessing the risk over specific time frames and …

Mortality risk in patients with dementia treated with antipsychotics versus other psychiatric medications

HC Kales, M Valenstein, HM Kim… - American Journal of …, 2007 - Am Psychiatric Assoc
Objective: Mortality rates in the year following new antipsychotic medication starts for
neuropsychiatric symptoms of dementia were compared with rates after starts of other …

Antipsychotic drug use and mortality in older adults with dementia

SS Gill, SE Bronskill, SLT Normand… - Annals of internal …, 2007 - acpjournals.org
Background: Antipsychotic drugs are widely used to manage behavioral and psychological
symptoms in dementia despite concerns about their safety. Objective: To examine the …

Risk of death with atypical antipsychotic drug treatment for dementia: meta-analysis of randomized placebo-controlled trials

LS Schneider, KS Dagerman, P Insel - Jama, 2005 - jamanetwork.com
ContextAtypical antipsychotic medications are widely used to treat delusions, aggression,
and agitation in people with Alzheimer disease and other dementia; however, concerns …

Neither atypical nor conventional antipsychotics increase mortality or hospital admissions among elderly patients with dementia: a two-year prospective study

MM Raivio, JV Laurila, TE Strandberg, RS Tilvis… - The American journal of …, 2007 - Elsevier
Background Antipsychotics are widely used to manage behavioral disorders in patients with
dementia. Recently, serious concerns have been raised about the stroke and mortality risk of …

[HTML][HTML] Risk of death in elderly users of conventional vs. atypical antipsychotic medications

PS Wang, S Schneeweiss, J Avorn… - … England Journal of …, 2005 - Mass Medical Soc
Background Recently, the Food and Drug Administration (FDA) issued an advisory stating
that atypical antipsychotic medications increase mortality among elderly patients. However …

Increased all-cause mortality by antipsychotic drugs: updated review and meta-analysis in dementia and general mental health care

SJ Ralph, AJ Espinet - Journal of Alzheimer's disease reports, 2018 - content.iospress.com
It is almost ten years since the Banerjee 2009 report established that inappropriate
prescribing of antipsychotics in the elderly was occurring in the UK and such patients had an …

FDA warns antipsychotic drugs may be risky for elderly

BM Kuehn - Jama, 2005 - jamanetwork.com
TREATMENT WITH ATYPICAL ANTI-psychotic drugs may cause a nearly 2-fold increase in
the rate of death in elderly dementia patients, warned the Food and Drug Administration …