Background: Intracellular pathogens avoid lysosomal targeting but recruit lysosome-
associated membrane protein 1 (LAMP1), the mechanism of which remains unclear …

Several intracellular pathogens have developed diverse strategies to avoid targeting to
lysosomes. However, they universally recruit lysosome-associated membrane protein 1 …

Salmonella is an intracellular bacterial pathogen that replicates within a membrane-bound
vacuole in host cells. The major lysosomal membrane proteins 1 and 2 (LAMP-1 and LAMP …

Lysosomes are cellular organelles containing diverse classes of catabolic enzymes that are
implicated in diverse cellular processes including phagocytosis, autophagy, lipid transport …

Our previous study showed that OmpA-deficient Salmonella Typhimurium failed to retain
LAMP-1 around the Salmonella-containing vacuoles (SCV), and escaped in to the host cell …

Phagocytosis is a process by which invading organisms are taken up by macrophages and
targeted to the lysosomes, where they are degraded. However, many pathogens modulate …

Salmonella genus encompasses Gram-negative, rod-shaped, facultative anaerobic, non-
sporulating, and predominantly motile enteric bacteria. It causes pathogenesis in a wide …

The host endolysosomal compartment is often manipulated by intracellular bacterial
pathogens. Salmonella (Salmonella enterica serovar Typhimurium) secrete numerous …

The host endolysosomal compartment is often manipulated by intracellular bacterial
pathogens. Salmonella (Salmonella enterica serovar Typhimurium) secrete numerous …

Salmonella enterica is an intracellular bacterial pathogen that replicates within membrane-
bound vacuoles through the action of effector proteins translocated into host cells …