The mammalian piriform cortex receives direct synaptic input from the olfactory bulb and is
likely the locus for the formation of odor percept. It remains unclear how individual cortical …

Spatial and temporal activity patterns of olfactory bulb projection neurons underlie the initial
representations of odors in the brain. However, olfactory perception ultimately requires the …

In primary sensory cortices, there are two main sources of excitation: afferent sensory input
relayed from the periphery and recurrent intracortical input. Untangling the functional roles of …

Odors activate distributed ensembles of neurons within the piriform cortex, forming cortical
representations of odor thought to be essential to olfactory learning and behaviors. This odor …

Increased understanding of the early stages of olfaction has lead to a renewed interest in the
higher brain regions responsible for forming unified 'odor images' from the chemical …

Much data on the olfactory bulb (OB) indicates that structural characteristics of odorant
molecules are encoded as ordered, spatially consolidated sets of active cells. New results …

Neurons in the neocortex exhibit spontaneous spiking activity in the absence of external
stimuli, but the origin and functions of this activity remain uncertain. Here, we show that …

Current models of odor discrimination in mammals involve molecular feature detection by a
large family of diverse olfactory receptors, refinement of molecular feature extraction through …

In awake rodents, the neural representation of olfactory information in the olfactory bulb is
largely dependent on brain state and behavioral context. Learning-modified neural plasticity …

Exposure to odorants results in a rapid (< 10 s) reduction in odor-evoked activity in the rat
piriform cortex despite relatively maintained afferent input from olfactory bulb mitral cells. To …