Primary Sjögren's syndrome is a complex autoimmune disorder, considered to represent an
ideal disease with which to study the mechanisms underlying autoimmunity because its …

Sjögren's syndrome is a chronic autoimmune disease characterised by progressive injury to
exocrine glands accompanied by diverse extra-glandular manifestations. The spectrum of …

The evidence for a strong genetic component conferring susceptibility to primary Sjögren's
syndrome (SS) is mounting. Several associations with SS have been reported and provide …

Pathogenesis of Sjögren's syndrome and therapeutic consequen... : Current Opinion in
Rheumatology Pathogenesis of Sjögren's syndrome and therapeutic consequences : Current …

In view of the new possibilities for the treatment of primary Sjögren's syndrome (pSS) given
by the availability of new biotechnological agents targeting the various molecular and …

Why should we explore and study disease mechanisms? This is particularly important when
we are dealing with complex pathogenesis without a direct causal agent, for example …

The pathogenesis of primary Sjögren's syndrome is complex and the factors initiating and
driving autoimmunity in this entity are largely unknown. Recent studies provide new insights …

In primary Sjögren syndrome (pSS), chronic inflammation of exocrine glands results in tissue
destruction and sicca symptoms, primarily of the mouth and eyes. Fatigue, arthralgia and …

Biological abnormalities associated with B lymphocytes are a hallmark of patients with
primary Sjögren's syndrome. Those patients present abnormal distribution of B lymphocytes …

Sjögren's syndrome (SS) is a rheumatic disease in which the salivary and lacrimal glands
are the principal targets of a pathologic autoimmune reaction. SS is manifested by …