Natural and bioprosthetic heart valves suffer from calcification, despite their differences in
etiology and tissue material. The mechanism of developing calcific deposits in valve tissue is …

The purpose of this study was to characterize the physicochemical properties of calcific
deposits that cause the failure of tissue‐derived heart valve bioprostheses. This was done in …

This investigation was performed to provide a comprehensive physicochemical
characterization of calcific deposits (CDs) that form on human heart valves under various …

Bioprosthetic heart valve tissue and associated calcification were studied in their natural
state, using environmental scanning electron microscopy (ESEM). Energy dispersive X‐ray …

While calcification of bioprosthetic valves presents a clinical problem, the mechanism of
formation of calcific deposits in the leaflets remains unclear. A new method for in vitro …

A model system was developed for the in vitro quantitative investigation of the calcification
process occurring in heart valves. The process of heart valve calcification consists of the …

Calcification is the most common cause of damage and subsequent failure of heart valves.
Although it is a common phenomenon, little is known about it, and less about the inorganic …

Calcification is still a major cause of failure of implantable biomaterials. A fast and reliable in
vitro model could contribute to the study of its mechanisms and to testing different …

Calcification is a recurrent problem in patients suffering from heart valve disease and it is the
main cause of failure in biological heart valve prostheses. The development of reliable …

Attempts to replace diseased human valves with prostheses began more than 30 yrs ago.
Heart valve prostheses can be broadly classified into mechanical prostheses (made out of …