Controlled release of diphosphonate to inhibit bioprosthetic heart valve calcification: dose-response and mechanistic studies

G Golomb, R Langer, FJ Schoen, MS Smith… - Journal of controlled …, 1986 - Elsevier
Calcification is the Principal cause of the clinical faliure of bioprosthetic heart valves (BHV)
fabricated from glutaraldehy de-treated porcine valves or bovine pericardium. This study …
被引用次数：70 相关文章 所有 4 个版本

Prevention of calcification of bioprosthetic heart valve leaflets by Ca2+ diphosphonate pretreatment

TP Johnston, FJ Schoen, RJ Levy - Journal of pharmaceutical …, 1988 - Wiley Online Library
Calcification frequently causes failure of bioprosthetic heart valves (BHV) fabricated from
glutaraldehyde‐pretreated porcine aortic valve or bovine pericardium. Systemic …
被引用次数：36 相关文章 所有 8 个版本
[PDF] wiley.com

Controlled-release drug delivery of diphosphonates to inhibit bioprosthetic heart valve calcification: release rate modulation with silicone matrices via drug solubility …

G Golomb, M Dixon, MS Smith, FJ Schoen… - Journal of …, 1987 - Elsevier
Calcification (CALC) is the most frequent cause of the clinical failure of bioprosthetic heart
valves (BHV) fabricated from glutaraldehyde pretreated porcine aortic valves or bovine …
被引用次数：96 相关文章 所有 9 个版本
[PDF] umich.edu

Controlled release of 1-hydroxyethylidene diphosphonate: in vitro assessment and effects on bioprosthetic calcification in sheep tricuspid valve replacements

TP Johnston, EL Bove, SF Bolling, JA Boyd… - International journal of …, 1989 - Elsevier
Calcification (CALC) is the most frequent cause of the clinical failure of bioprosthetic valves
(BHV's). Controlled-release (paravalvar) administration of the anticalcification agent …
被引用次数：20 相关文章 所有 6 个版本
[PDF] umich.edu

Controlled release of ethanehydroxy diphosphonate from polyurethane reservoirs to inhibit calcification of bovine pericardium used in bioprosthetic heart valves

TP Johnston, JA Boyd, BL Ciesliga, FJ Schoen… - International journal of …, 1990 - Elsevier
Calcification (CALC) of bioprosthetic heart valves (BHVs) fabricated from either
glutaraldehyde-pretreated bovine pericardial tissue or porcine aortic valves is the most …
被引用次数：21 相关文章 所有 6 个版本
[PDF] umich.edu

Site-specific delivery of ethanehydroxy diphosphonate from refillable polyurethane reservoirs to inhibit bioprosthetic tissue calcification

TP Johnston, CL Webb, FJ Schoen, RJ Levy - Journal of controlled release, 1993 - Elsevier
Calcification (CALC) is the most frequent cause for the failure of bioprosthetic heart valves
fabricated from glutaraldehyde-pretreated porcine aortic valve, and contributes to the failure …
被引用次数：15 相关文章 所有 4 个版本
[PDF] psu.edu

Controlled release of diphosphonates from synthetic polymers to inhibit calcification

G Golomb - Journal of biomaterials applications, 1987 - journals.sagepub.com
Calcification is the most frequent cause of the failure of bioprosthetic heart valves fabricated
from glutaraldehyde pretreated porcine aortic valves or bovine pericardium. Formulation and …
被引用次数：24 相关文章 所有 8 个版本
[PDF] sciencedirect.com

Prevention of leaflet calcification of bioprosthetic heart valves with diphosphonate injection therapy: experimental studies of optimal dosages and therapeutic durations

RJ Levy, FJ Schoen, SA Lund, MS Smith - The Journal of Thoracic and …, 1987 - Elsevier
Ethanehydroxydiphosphonate therapy was studied for prevention of calcification of
bioprosthetic heart valve cusps (from glutaraldehyde-preserved porcine aortic valves) …
被引用次数：76 相关文章 所有 6 个版本
[PDF] annalsthoracicsurgery.org

Inhibition of bioprosthetic heart valve calcification with aminodiphosphonate covalently bound to residual aldehyde groups

CL Webb, JJ Benedict, FJ Schoen, JA Linden… - The Annals of thoracic …, 1988 - Elsevier
Calcification is the principal mode of failure of bioprosthetic heart valves (BPHV) fabricated
from glutaraldehyde-pretreated porcine aortic valves or bovine pericardium. Covalent …
被引用次数：90 相关文章 所有 10 个版本
[PDF] umich.edu

Synergistic inhibition of the calcification of glutaraldehyde pretreated bovine pericardium in a rat subdermal model by FeCl3 and ethanehydroxydiphosphonate: pre …

D Hirsch, J Drader, YV Pathak, R Yee, FJ Schoen… - Biomaterials, 1993 - Elsevier
Calcification is a frequent cause of the clinical failure of bioprosthetic heart valves fabricated
from glutaraldehyde-pretreated porcine aortic valves or glutaraldehyde-pretreated bovine …
被引用次数：28 相关文章 所有 6 个版本