Neuroprotective effects of pomegranate peel extract after chronic infusion with amyloid-β peptide in mice

MC Morzelle, JM Salgado, M Telles, D Mourelle… - PloS one, 2016 - journals.plos.org
Alzheimer's disease is a chronic and degenerative condition that had no treatment until
recently. The current therapeutic strategies reduce progression of the disease but are …

Pomegranate extract modulates processing of amyloid-β precursor protein in an aged Alzheimer's disease animal model

A H. Ahmed, G M. Subaiea, A Eid, L Li… - Current Alzheimer …, 2014 - benthamdirect.com
Accumulating research supports the neuroprotective effects of pomegranate (Punica
granatum) juice and extracts against Alzheimer's disease (AD) but there is limited data …

Pomegranate juice decreases amyloid load and improves behavior in a mouse model of Alzheimer's disease

RE Hartman, A Shah, AM Fagan, KE Schwetye… - Neurobiology of …, 2006 - Elsevier
Although there are no proven ways to delay onset or slow progression of Alzheimer's
disease (AD), studies suggest that diet can affect risk. Pomegranates contain very high …

[HTML][HTML] Pomegranate polyphenols and extract inhibit nuclear factor of activated T-cell activity and microglial activation in vitro and in a transgenic mouse model of …

L Rojanathammanee, KL Puig, CK Combs - The Journal of nutrition, 2013 - Elsevier
Alzheimer disease (AD) brain is characterized by extracellular plaques of amyloid β (Aβ)
peptide with reactive microglia. This study aimed to determine whether a dietary intervention …

[HTML][HTML] Consumption of pomegranates improves synaptic function in a transgenic mice model of Alzheimer's disease

N Braidy, MM Essa, A Poljak, S Selvaraju, S Al-Adawi… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Alzheimer's Disease (AD) is a progressive neurodegenerative disorder characterized by
extracellular plaques containing abnormal Amyloid Beta (Aβ) aggregates, intracellular …

An insight into the neuroprotective effects and molecular targets of pomegranate (Punica granatum) against Alzheimer's disease

N George, M AbuKhader, K Al Balushi… - Nutritional …, 2023 - Taylor & Francis
Alzheimer's disease (AD) is a progressive neurodegenerative disease that still has no
permanent cure. The drugs prescribed in the present days are only for symptomatic relief for …

Pomegranate (Punica granatum L.) Attenuates Neuroinflammation Involved in Neurodegenerative Diseases

A Mehdi, B Lamiae, B Samira, M Ramchoun… - Foods, 2022 - mdpi.com
Food scientists have studied the many health benefits of polyphenols against pernicious
human diseases. Evidence from scientific studies has shown that earlier healthy lifestyle …

Long-term dietary supplementation of pomegranates, figs and dates alleviate neuroinflammation in a transgenic mouse model of Alzheimer's disease

MM Essa, S Subash, M Akbar, S Al-Adawi… - PLoS …, 2015 - journals.plos.org
Alzheimer's disease (AD) is a devastating age-related neurodegenerative disease with no
specific treatment at present. The APPsw/Tg2576 mice exhibit age-related deterioration in …

Pomegranate polyphenol punicalagin improves learning memory deficits, redox homeostasis, and neuroinflammation in aging mice

P Chen, F Chen, J Lei, B Zhou - Phytotherapy Research, 2023 - Wiley Online Library
Alzheimer's disease (AD) is an irreversible, progressive brain disorder characterized by loss
of memory and cognitive dysfunction in the aged. Despite remarkable advances in drug …

Long-term (15 mo) dietary supplementation with pomegranates from Oman attenuates cognitive and behavioral deficits in a transgenic mice model of Alzheimer's …

S Subash, N Braidy, MM Essa, AB Zayana, V Ragini… - Nutrition, 2015 - Elsevier
Abstract Objective Transgenic (Tg) mice, which possess an amyloid precursor protein (APP)
gene mutation, develop extracellular amyloid β (Aβ) deposition in the brain, and severe …