Modeling stochastic variability in the numbers of surviving Salmonella enterica, enterohemorrhagic Escherichia coli, and Listeria monocytogenes cells at the single …

K Koyama, H Hokunan, M Hasegawa… - Applied and …, 2017 - Am Soc Microbiol
Despite effective inactivation procedures, small numbers of bacterial cells may still remain in
food samples. The risk that bacteria will survive these procedures has not been estimated …

Transforming kinetic model into a stochastic inactivation model: Statistical evaluation of stochastic inactivation of individual cells in a bacterial population

S Hiura, H Abe, K Koyama, S Koseki - Food microbiology, 2020 - Elsevier
Kinetic models performing point estimation are effective in predicting the bacterial behavior.
However, the large variation of bacterial behavior appearing in a small number of cells, ie …

Estimation of the probability of bacterial population survival: development of a probability model to describe the variability in time to inactivation of Salmonella enterica

K Koyama, H Hokunan, M Hasegawa, S Kawamura… - Food …, 2017 - Elsevier
Despite the development of numerous predictive microbial inactivation models, a model
focusing on the variability in time to inactivation for a bacterial population has not been …

Do bacterial cell numbers follow a theoretical Poisson distribution? Comparison of experimentally obtained numbers of single cells with random number generation …

K Koyama, H Hokunan, M Hasegawa, S Kawamura… - Food …, 2016 - Elsevier
We investigated a bacterial sample preparation procedure for single-cell studies. In the
present study, we examined whether single bacterial cells obtained via 10-fold dilution …

Individual cell heterogeneity as variability source in population dynamics of microbial inactivation

Z Aspridou, KP Koutsoumanis - Food microbiology, 2015 - Elsevier
A statistical modeling approach was applied for describing and evaluating the individual cell
heterogeneity as variability source in microbial inactivation. The inactivation data (N t vs …

Recent advances in predictive microbiology: theory and application of conversion from population dynamics to individual cell heterogeneity during inactivation …

S Koseki, K Koyama, H Abe - Current Opinion in Food Science, 2021 - Elsevier
Highlights•Development of stochastic modeling technique for bacterial inactivation is
reviewed.•Variability in survival cell numbers during inactivation process is described as …

Calculating stochastic inactivation of individual cells in a bacterial population using variability in individual cell inactivation time and initial cell number

K Koyama, H Abe, S Kawamura, S Koseki - Journal of Theoretical Biology, 2019 - Elsevier
The traditional log-linear inactivation kinetics model considers microbial inactivation as a
process that follows first-order kinetics. A basic concept of log reduction is decimal reduction …

Stochastic simulation for death probability of bacterial population considering variability in individual cell inactivation time and initial number of cells

K Koyama, H Abe, S Kawamura, S Koseki - International journal of food …, 2019 - Elsevier
Decimal reduction time (D-value) based on the first-order survival kinetics model is not
sufficient for reliable estimation of the bacterial survivors of inactivation treatment because …

Modeling bacterial survival in unfavorable environments

RC Whiting - Journal of Industrial Microbiology, 1993 - Springer
The long-term survival of pathogenic microorganisms was evaluated and modeled in
simulated fermented and dried, uncooked sausages, such as salami and pepperoni. Listeria …

Stochastic evaluation of Salmonella enterica lethality during thermal inactivation

H Abe, K Koyama, S Kawamura, S Koseki - International journal of food …, 2018 - Elsevier
Stochastic models take into account the uncertainty and variability of predictions in
quantitative microbial risk assessment. However, a model that considers thermal inactivation …