Epithelial cells lose their usual polarization during carcinogenesis. Although most malignant
tumours are of epithelial origin little is known about ion channels in carcinoma cells …

Abstract Migration of transformed Madin-Darby canine kidney (MDCK-F) cells depends on
the polarized activity of a Ca 2+-sensitive K+ channel. We tested whether a gradient of …

Madin Darby canine kidney cells transformed by alkaline stress (MDCK-F cells)
constitutively migrate at a rate of about 1 μm· min–1. Migration depends on the intermittent …

Previously, we showed that migration of transformed renal epithelial cells (MDCK-F cells) is
a K+ channel-dependent process [J Clin Invest 1994; 93: 1631]. In order to determine …

Migration plays an important role in the formation of tumor metastases. Nonetheless, little is
known about electrophysiological phenomena accompanying or underlying migration …

In this article we review aspects of plasticity of renal epithelial cells. We focus on one
particular feature, namely on cell migration. For normal renal and other epithelial cells …

Cell migration of transformed renal epithelial cells (MDCK-F) depends–in addition to
cytoskeletal mechanisms–on the polarized activity of a Ca2+-sensitive K+ channel in the …

Migration of transformed renal epithelial cells (transformed Madin-Darby canine kidney cells,
MDCK-F cells) relies on the activity of a Ca 2+-sensitive K+ channel (IK channel) that is more …

Migration of transformed renal epithelial (MDCK-F) cells depends on the polarized activity of
a Ca 2+-sensitive K+ channel (IK channel; Pflügers Arch 432: R87–R93, 1996). This study …

Our aim is to establish whether Madin-Darby canine kidney (MDCK) cells have polarized ion
channels. We first observe that cation currents are almost exclusively carried by K+; Na+ and …