Background• An electronic literature search was performed by one reviewer using the
PubMed database on April 7, 2020 with the following search terms (apremilast AND …

Introduction: Psoriasis is a chronic inflammatory skin disease characterized by dysregulation
of the immune system and release of pro-inflammatory mediators. Drugs available for …

Objectives The aim of this paper is to present our personal as well as literature-sourced real-
world evidenced on apremilast use in psoriasis patients with serious baseline comorbidities …

Aim: We have conducted a systematic review and meta-analysis to explore the influence of
apremilast on treatment efficacy for psoriasis. Material and methods: We have searched …

Background The evidence for adding small-molecule drugs to an ongoing biologic treatment
is sparse, but combination therapies appear to be advantageous in appropriately selected …

Objective: To review the pharmacology, efficacy, and safety of apremilast and determine its
role relative to other agents in the treatment of psoriasis and psoriatic arthritis. Data Sources …

Materials and Methods: This was retrospective, single-center, longitudinal, observational
cohort study where the total study period was 24 weeks. Effectiveness parameters were the …

INTRODUCTION: Many options are available for patients with moderate to severe plaque
psoriasis. Patients with moderate disease, however, are often undertreated and do not …

Apremilast is a small molecule approved for the treatment of plaques psoriasis and adult
psoriatic arthritis. Pivotal studies have demonstrated short and long term efficacy and safety …

Small molecule medications like apremilast are emerging as promising options for patients
with psoriasis and other inflammatory conditions. Apremilast was approved by the Food and …