Persistent inflammation during anti-tuberculosis treatment with diabetes comorbidity

NP Kumar, KF Fukutani, BS Shruthi, T Alves… - Elife, 2019 - elifesciences.org
Diabetes mellitus (DM) increases risk for pulmonary tuberculosis (TB) and adverse treatment
outcomes. Systemic hyper-inflammation is characteristic in people with TB and concurrent …

Effects of diabetes mellitus on the clinical presentation and treatment response in tuberculosis

CC Leung, WW Yew, TYW Mok, KS Lau, CF Wong… - …, 2017 - Wiley Online Library
Background and objective With the colliding global epidemics of diabetes mellitus (DM) and
tuberculosis (TB), we studied the effects of DM on the presentation of TB and its response to …

Systems immunology of diabetes-tuberculosis comorbidity reveals signatures of disease complications

CA Prada-Medina, KF Fukutani, N Pavan Kumar… - Scientific reports, 2017 - nature.com
Comorbid diabetes mellitus (DM) increases tuberculosis (TB) risk and adverse outcomes but
the pathological interactions between DM and TB remain incompletely understood. We …

Slow radiological improvement and persistent low-grade inflammation after chemotherapy in tuberculosis patients with type 2 diabetes

A Mily, P Sarker, I Taznin, D Hossain, MA Haq… - BMC infectious …, 2020 - Springer
Background Diabetes mellitus type 2 (DM) may impede immune responses in tuberculosis
(TB) and thus contribute to enhanced disease severity. In this study, we aimed to evaluate …

[HTML][HTML] Sex differences in the impact of diabetes mellitus on tuberculosis recurrence: a retrospective national cohort study

D Eksombatchai, D Jeong, J Mok, D Jeon… - International Journal of …, 2023 - Elsevier
Objectives Whether diabetes mellitus (DM) increases tuberculosis (TB) recurrence risk is
debatable. We determined the effect of DM on TB recurrence. Methods This retrospective …

The association of diabetes and tuberculosis: impact on treatment and post-treatment outcomes

RN Sanghani, ZF Udwadia - Thorax, 2013 - thorax.bmj.com
We are approaching a day and age where the terms communicable and noncommunicable
diseases are taking on a new meaning. In the epidemiology and global public health space …

Diabetes mellitus and tuberculosis treatment outcomes in Pune, India

V Mave, S Gaikwad, M Barthwal… - Open forum …, 2021 - academic.oup.com
Background Diabetes mellitus (DM) increases the risk of tuberculosis (TB) disease.
Knowledge of the impact of DM on TB treatment outcomes is primarily based on …

The influence of diabetes, glycemic control, and diabetes-related comorbidities on pulmonary tuberculosis

CY Chiang, KJ Bai, HH Lin, ST Chien, JJ Lee… - PloS one, 2015 - journals.plos.org
Background To assess the influence of diabetes mellitus (DM), glycemic control, and
diabetes-related comorbidities on manifestations and outcome of treatment of pulmonary …

Diabetes and risk of tuberculosis relapse: nationwide nested case-control study

PH Lee, HC Lin, ASE Huang, SH Wei, MS Lai, HH Lin - PloS one, 2014 - journals.plos.org
The aim of this study was to investigate the association between diabetes mellitus (DM) and
tuberculosis (TB) relapse using the nationwide TB registry in Taiwan. We conducted a case …

Effect of standard tuberculosis treatment on naive, memory and regulatory T‐cell homeostasis in tuberculosis–diabetes co‐morbidity

NP Kumar, K Moideen, V Viswanathan… - …, 2016 - Wiley Online Library
Perturbations in CD 4+ and CD 8+ T‐cell phenotype and function are hallmarks of
tuberculosis–diabetes co‐morbidity. However, their contribution to the pathogenesis of this …