Dihydrotestosterone concentrations have been measured in prostatic tissue from patients
with recurrent advanced prostatic cancer after 1.0 to 5.0 mg. diethylstilbestrol per day or …

Because it is well known that prostatic cancer is dependent on testosterone, and that
dihydrotestosterone is the active mediator of the androgen action in the prostatic cell, we …

METHODS Patients at Wadsworth Veterans Hospital were classified into the stage of their
disease according to established criteria. 12 Twenty-eight patients with stage 3 or 4 disease …

RESULTS Pre-treatment testosterone levels. Among the 68 patients with stage III disease
the plasma testosterone was 0.56 plus or minus 0.257 µg. per 100 ml.(mean plus or minus …

The dihydrotestosterone content of normal peripheral and benign hyperplastic prostates was
measured in tissue obtained at open surgical procedures on 29 men of ages 36 to 82 yr. The …

Orchiectomy is often used in the management of metastatic adenocarcinoma of the prostate,
an androgen dependent tumour, since it markedly reduces the concentrations of plasma …

We compared the effect of a variety of drug regiments to lower prostate DHT concentration.
Patients with BPH were treated for one week prior to surgery with either tamoxifen, flutamide …

Tissue dihydrotestosterone and 5α-reductase (Δ4-3-ketosteroid-5α-oxidoreductase) levels
have been measured in prostates of patients with cancer and benign prostatic hypertrophy; …

Abstract From June 1982 to February 1985, 53 patients with stage D2 carcinoma of the
prostate confirmed by tissue biopsy, elevated prostatic acid phosphatase and a positive …

Dihydrotestosterone (DHT) levels were measured by RIA in tumor tissue from 32 men with
advanced prostate cancer and correlated with their clinical responses to antiandrogen …