ABSTRACT Background: Sickle Cell Anaemia (SCA) is the commonest genetic disorder
affecting the black race globally. Nigeria has the highest SCA burden of any country …

Background: Sickle cell disease (SCD) is the most common monogenetic disorder
worldwide. With an annual birthrate of approximately 150,000 in Nigeria, the burden is …

Background: Advancement in medical management and diagnosis has seen a rise in the
population of Sickle Cell Anaemia (SCA) patient reaching adulthood, albeit increased …

Background: The clinical severity of sickle cell anemia (SCA) varies from one individual to
another. Several factors, including genetic predisposition, environmental and social factors …

Background: There are documented established markers (indices) of disease severity in
patients with sickle cell anemia (SCA) and they determine the course of the disease. This …

Sickle cell disease (SCD) is a monogenic red blood cell disorder of public health importance
globally, with a high prevalence in Africa. Accurate estimation of population affected by the …

Renal abnormalities in adult Nigerians with sickle cell anemia (SCA) have not been
extensively studied. To determine the prevalence, pattern and the associated risk factors of …

Background Anaemia in sickle cell disease (SCD) is a significant cause of morbidity and
mortality, but few studies have reported on the burden and outcome of very severe anaemia …

Aims: To determine the pattern and associated risk factors for musculoskeletal complications
among sickle cell anaemia patients in South-east Nigeria. Methodology: A retrospective …

BACKGROUND: Sickle cell anaemia (SCA) is a chronic multi-systemic condition
characterized by haemoglobin polymerization leading to erythrocytes rigidity, frequent …