Pathogenesis of Sjögren's syndrome

K Yamamoto - Autoimmunity reviews, 2003 - Elsevier
The pathogenesis of Sjögren's syndrome is poorly understood. Genetic and environmental
factors appear to contribute to the development of this syndrome. Viral infection is one of the …

Immunologic abnormalities in Sjögren's syndrome

HM Moutsopoulos, N Talal - Sjögren's syndrome: Clinical and …, 1987 - Springer
The field of autoimmunity, like immunology itself, is undergoing rapid change due to
progress in cellular immunology and molecular biology. The old concept that individuals are …

Immunopathogenesis of Sjögren's syndrome

AT Borchers, SM Naguwa, CL Keen… - Clinical Reviews in …, 2003 - Springer
Sjögren's syndrome (SS) is an autoimmune disease characterized by the sicca symptoms of
dry eyes and dry mouth. Glandular dysfunction is thought to arise from destruction …

B-cell lymphoproliferation in primary Sjögren's syndrome.

AG Tzioufas - Clinical and experimental rheumatology, 1996 - europepmc.org
Sjögren's syndrome (SS) is characterized by lymphocytic infiltration of the exocrine glands,
along with a polyclonal B-cell activation which is illustrated by the presence of multiple …

Sjögren's syndrome: autoantibodies to cellular antigens: clinical and molecular aspects

CP Mavragani, AG Tzioufas… - International archives of …, 2000 - karger.com
Autoantibodies to cellular autoantigens are usually found in sera of patients with systemic
autoimmune rheumatic diseases. Patients with Sjögren's syndrome (SS) frequently present …

The spectrum of benign to malignant lymphoproliferation in Sjögren's syndrome

LG Anderson, N Talal - Clinical and Experimental Immunology, 1972 - ncbi.nlm.nih.gov
Clinical and pathological evidence suggests that a wide spectrum of lymphoproliferation
exists in Sjögren's syndrome (SS), from benign disease with lymphoid infiltrates confined to …

Pathogenesis of Sjögren's syndrome

RI Fox, HI Kang - Rheumatic Disease Clinics of North America, 1992 - Elsevier
Sjögren's syndrome is a systemic autoimmune disease characterized by lymphocytic
infiltrations of lacrimal and salivary glands. SS patients produce a variety of autoantibodies …

The complexity of Sjögren's syndrome: novel aspects on pathogenesis

R Jonsson, P Vogelsang, R Volchenkov, A Espinosa… - Immunology letters, 2011 - Elsevier
In Sjögren's syndrome, like in most other autoimmune diseases, the enigma leading to a
pathogenic attack against self has not yet been solved. By definition, the disease must be …

Sjögren's syndrome

SA Papiris, IA Tsonis… - Seminars in respiratory …, 2007 - thieme-connect.com
Sjögren's syndrome (SS) is a chronic, slowly progressive, inflammatory, autoimmune
disease characterized by (1) lymphocytic infiltration of the exocrine glands leading to …

New developments in Sjögren's syndrome

HM Moutsopoulos, P Youinou - Current opinion in rheumatology, 1991 - journals.lww.com
Over the past months, noteworthy contributions to our understanding of the clinical
manifestations of Sjögren's syndrome have been made. Scintigraphic and echographic …