Huntington's disease is an inherited disorder caused by expansion of a CAG trinucleotide
repeat in the IT15 gene, which leads to expansion of a polyglutamine tract within the protein …

Huntington disease (HD) is an autosomal dominant neurodegenerative disorder with midlife
onset characterized by psychiatric, cognitive, and motor symptoms. Death occurs between …

The Huntington disease (HD) phenotype is associated with expansion of a trinucleotide
repeat in the IT15 gene, which is predicted to encode a 348-kDa protein named huntington …

Huntington's disease (HD) is caused by a genetic mutation that results in a polyglutamine
expansion in huntingtin. The time course of neuronal loss in the HD striatum and other …

Huntington's disease (HD) results from the expansion of a polyglutamine encoding CAG
repeat in a gene of unknown function. The wide expression of this transcript does not …

Huntington's disease is characterized by a loss of brain striatal neurons that occurs as a
consequence of an expansion of a CAG repeat in the huntingtin protein. The resulting …

Huntington's disease (HD) is an inherited, autosomal dominant, neurodegenerative disorder
characterized by involuntary choreiform movements, cognitive decline and a progressive …

The immunohistochemical localization of huntingtin was examined in the Huntington's
disease (HD) brain with an antibody that recognizes the wild‐type and mutant proteins …

Huntington Disease (HD) results from polyglutamine expansion within the N-terminus of
huntingtin. We have produced yeast artificial chromosome (YAC) transgenic mice …

Huntington's disease (HD) is an inherited, neurodegenerative disorder caused by the
expansion of a glutamine repeat in the N-terminus of the huntingtin protein. To gain insight …