CXC motif chemokine receptor 2 (CXCR2) is G protein-coupled receptor (GPCR) and plays
important roles in various inflammatory diseases and cancers, including chronic obstructive …

The chemokine receptors CXCR1/2 and their ligand CXCL8 are essential for the activation
and trafficking of inflammatory mediators as well as tumor progression and metastasis. The …

There has been considerable in vivo evidence that chemokine receptor CXCR4 and its
endogenous ligand CXCL12 modulate some important physiological and …

Dysregulated leukocyte recruitment is believed to be a key contributor to various acute and
chronic inflammatory disorders which can lead to serious pathological consequences …

Recent findings have modified our understanding of the roles of chemokine receptor CXCR2
and its ligands in cancer, inflammation, and immunity. Studies in Cxcr2 tissue-specific …

The CXCR3 chemokine receptor was first discovered in 1996 and has been shown to play
an important role in several diseases, most of which are related to inflammation. This review …

Chemokines, binding their various G protein-coupled receptors, lead the way for leukocytes
in health and inflammation. Yet chemokine receptor expression is not limited to leukocytes …

Inflammation is the body's defense response to exogenous or endogenous stimuli, involving
complex regulatory mechanisms. Discovering anti‐inflammatory drugs with both …

Leukocyte recruitment to sites of infection or tissue damage plays a crucial role for the innate
immune response. Chemokine-dependent signaling in immune cells is a very important …

The CXC chemokine receptor 4 (CXCR4) is a highly reserved G-protein coupled 7-
transmembrane (TM) chemokine receptor which consists of 352 amino acids. CXCR4 has …