Bacterial chemoreceptors mediate chemotactic responses to diverse stimuli. Here, by using
an integrated in silico, in vitro, and in vivo approach, we screened a large compound library …

The methyl-accepting chemotaxis proteins are a family of receptors in bacteria that mediate
chemotaxis to diverse signals. To explore the plasticity of these proteins, we have developed …

Most bacteria use transmembrane sensors to detect a wide range of environmental stimuli. A
large class of such sensors are the chemotaxis receptors used by motile bacteria to follow …

Bacteria use chemotaxis signaling pathways to sense environmental changes. Escherichia
coli chemotaxis system represents an ideal model that illustrates fundamental principles of …

Baseline signal output and communication between the periplasmic and cytoplasmic
domains of the Escherichia coli aspartate chemoreceptor Tar Ec are both strongly influenced …

The chemoreceptors of Escherichia coli are homodimeric membrane proteins that cluster in
patches near the cell poles. They convert environmental stimuli into intracellular signals that …

Bacterial chemotaxis signaling is triggered by binding of chemo-effectors to the membrane-
bound chemoreceptor dimers. Though much is known about the structure of the …

The Tap (taxis toward peptides) receptor and the periplasmic dipeptide-binding protein
(DBP) of Escherichia coli together mediate chemotactic responses to dipeptides. Tap is a …

Signalling through chemosensory pathways is typically initiated by the binding of signal
molecules to the chemoreceptor ligand binding domain (LBD). The PcaY_PP …

Transmembrane bacterial chemoreceptors are extended, rod-shaped homodimers with
ligand-binding sites at one end and interaction sites for signaling complex formation and …