Dendritic spines shaped by synaptic activity

M Segal, P Andersen - Current opinion in neurobiology, 2000 - Elsevier
A recent series of exciting observations, using novel high-resolution time-lapse imaging of
living cells, has provoked a major shift in our understanding of the dendritic spine, from a …

Rapid plasticity of dendritic spine: hints to possible functions?

M Segal - Progress in neurobiology, 2001 - Elsevier
Contrary to a century-old belief that dendritic spines are stable storage sites of long term
memory, the emerging picture from a recent flurry of exciting observations using novel high …

Dentritic spines: structure, dynamics and regulation

H Hering, M Sheng - Nature Reviews Neuroscience, 2001 - nature.com
Dendritic spines are tiny protrusions that receive excitatory synaptic input and
compartmentalize postsynaptic responses. Heterogeneous in size and shape, and …

Dendritic spine formation and pruning: common cellular mechanisms?

M Segal, E Korkotian, DD Murphy - Trends in neurosciences, 2000 - cell.com
The recent advent of novel high-resolution imaging methods has created a flurry of exciting
observations that address a century-old question: what are biological signals that regulate …

Dendritic spine geometry: functional implication and regulation

Y Hayashi, AK Majewska - Neuron, 2005 - cell.com
Dendritic spines are tiny protrusions on dendritic shafts where most excitatory synapses are
located. Recent advances in imaging technologies have given us great insight into the …

Structural plasticity of dendritic spines

M Bosch, Y Hayashi - Current opinion in neurobiology, 2012 - Elsevier
Dendritic spines are small mushroom-like protrusions arising from neurons where most
excitatory synapses reside. Their peculiar shape suggests that spines can serve as an …

Postsynaptic signaling during plasticity of dendritic spines

H Murakoshi, R Yasuda - Trends in neurosciences, 2012 - cell.com
Dendritic spines, small bulbous postsynaptic compartments emanating from neuronal
dendrites, have been thought to serve as basic units of memory storage. Despite their small …

Dendritic spine plasticity: function and mechanisms

K Runge, C Cardoso, A De Chevigny - Frontiers in synaptic …, 2020 - frontiersin.org
Dendritic spines are small protrusions studding neuronal dendrites, first described in 1888
by Ramón y Cajal using his famous Golgi stainings. Around 50 years later the advance of …

Anatomical and physiological plasticity of dendritic spines

VA Alvarez, BL Sabatini - Annu. Rev. Neurosci., 2007 - annualreviews.org
In excitatory neurons, most glutamatergic synapses are made on the heads of dendritic
spines, each of which houses the postsynaptic terminal of a single glutamatergic synapse …

Dendritic spines: from structure to in vivo function

NL Rochefort, A Konnerth - EMBO reports, 2012 - embopress.org
Dendritic spines arise as small protrusions from the dendritic shaft of various types of neuron
and receive inputs from excitatory axons. Ever since dendritic spines were first described in …