W Alshaer, H Hillaireau, E Fattal - Advanced drug delivery reviews, 2018 - Elsevier
Aptamers are versatile nucleic acid-based macromolecules characterized by their high affinity and specificity to a specific target. Taking advantage of such binding properties …
F He, N Wen, D Xiao, J Yan, H Xiong… - Current medicinal …, 2020 - ingentaconnect.com
Aptamers are single-stranded DNA or RNA with 20-100 nucleotides in length that can specifically bind to target molecules via formed three-dimensional structures. These …
E Levy-Nissenbaum, AF Radovic-Moreno… - Trends in …, 2008 - cell.com
Nucleic acid ligands, also known as aptamers, are a class of macromolecules that are being used in several novel nanobiomedical applications. Aptamers are characterized by high …
S Venkatesan, K Chanda, MM Balamurali - ACS omega, 2023 - ACS Publications
Aptamers are chemical antibodies possessing the capability of overcoming the limitations posed by conventional antibodies, particularly for diagnostic, therapeutic, and theranostic …
A wide variety of nanomaterials have emerged in recent years with advantageous properties for a plethora of therapeutic and diagnostic applications. Such applications include drug …
W Tan, H Wang, Y Chen, X Zhang, H Zhu, C Yang… - Trends in …, 2011 - cell.com
The active targeting of drugs in a cell-, tissue-or disease-specific manner represents a potentially powerful technology with widespread applications in medicine, including the …
Aptamers are single-stranded oligonucleotides that specifically bind and interact with their corresponding targets, including proteins and cells, through unique three-dimensional …
H Zhu, J Li, XB Zhang, M Ye, W Tan - ChemMedChem, 2015 - Wiley Online Library
Aptamers are emerging as promising therapeutic agents and recognition elements. In particular, cell‐SELEX (systematic evolution of ligands by exponential enrichment) allows in …
Aptamer nanomedicine, including therapeutic aptamers and aptamer nanocomplexes, is beginning to fulfill its potential in both clinical trials and preclinical studies. Especially in …