Beneficial effects of caffeic acid phenethyl ester (CAPE) on the ischaemia-reperfusion injury in rat skin flaps

H Aydogan, A Gurlek, H Parlakpinar, I Askar… - Journal of plastic …, 2007 - Elsevier
BACKGROUND: Reperfusion injury is a phenomenon that occurs when tissues are
subjected to ischaemia for a variable period of time, after which they are reperfused. Many …

Caffeic acid phenetyl ester accelerates cutaneous wound healing in a rat model and decreases oxidative stress

G Serarslan, E Altuğ, T Kontas, E Atik… - Clinical and …, 2007 - academic.oup.com
Background. Cutaneous injury causes a depression in antioxidant status, as reactive oxygen
species (ROS) are produced in response to injury. Aim. To determine the effects of caffeic …

Pharmacologic enhancement of rat skin flap survival with topical oleic acid

OK Hsu, E Gabr, E Steward, H Chen… - Plastic and …, 2004 - journals.lww.com
This study was instituted to investigate in a rat model the effect of topical coadministration of
the penetration enhancer oleic acid (10% by volume) and RIMSO-50 (medical grade …

Caffeic acid phenethyl ester improves burn healing in rats through anti-inflammatory and antioxidant effects

JS Dos Santos… - Journal of Burn Care & …, 2013 - academic.oup.com
Although caffeic acid phenethyl ester (CAPE) has beneficial properties, its anti-inflammatory
and antioxidant effects on healing burn injury have not been investigated as yet. Female …

Prevention of ischemia-reperfusion injury in a rat skin flap model: the role of mast cells, cromolyn sodium, and histamine receptor blockade

PG Cordeiro, JJ Lee, D Mastorakos… - Plastic and …, 2000 - journals.lww.com
The objective of this study was to examine the role of mast cells and their principal product,
histamine, in ischemia/reperfusion injury. Cromolyn sodium, diphenhydramine, and …

Vitamin C reduces ischemia-reperfusion injury in a rat epigastric island skin flap model

A Zaccaria, N Weinzweig, M Yoshitake… - Annals of plastic …, 1994 - journals.lww.com
Free radicals have been implicated in the cause of ischemia-reperfusion injury. Various
agents have been used in an attempt to reduce ischemia-reperfusion injury …

Hydrogen-rich saline attenuates skin ischemia/reperfusion induced apoptosis via regulating Bax/Bcl-2 ratio and ASK-1/JNK pathway

YQ Liu, YF Liu, XM Ma, YD Xiao, YB Wang… - Journal of plastic …, 2015 - Elsevier
Introduction Many pathways have been reported involving the effect of hydrogen-rich saline
on protecting skin flap partial necrosis induced by the inflammation of ischemia/reperfusion …

Effects of pentoxyfilline and heparin on reperfusion injury island skin flaps in rats exposed to tobacco

FAS Freitas, CE Piccinato, J Cherri… - Journal of Surgical …, 2010 - Elsevier
BACKGROUND: Ischemia-reperfusion injury is believed to be a major cause of transferred
skin flap failure. Cigarette smoking is known to be associated with endogenous antioxidant …

Caffeic acid phenethyl ester: a review of its antioxidant activity, protective effects against ischemia-reperfusion injury and drug adverse reactions

MF Tolba, HA Omar, SS Azab, AE Khalifa… - Critical reviews in …, 2016 - Taylor & Francis
Propolis, a honey bee product, has been used in folk medicine for centuries for the treatment
of abscesses, canker sores and for wound healing. Caffeic acid phenethyl ester (CAPE) is …

Protective effect of grape seed extract against ischaemia/reperfusion injury in a rat epigastricflap model

O Karaaslan, MG Ulusoy, Y Kankaya… - Journal of plastic …, 2010 - Elsevier
Proanthocyanidins are potent natural antioxidants which belong to a class of polyphenols.
Proanthocyanidin-rich extracts are prepared from grape seeds. The effect of grape seed …