Amyloid precursor protein (APP) is a transmembrane glycoprotein that has been the subject
of intense research because of its implication in Alzheimer's disease. However, the …

The amyloid precursor protein (APP) is a transmembrane protein mostly recognized for its
association with Alzheimer's disease. The physiological function of APP is still not …

Amyloid precursor protein (APP) has been a focus of intense investigation because of its
role in Alzheimer's disease (AD), however, its biological function remains uncertain. Loss of …

Amyloid precursor protein (APP) plays a pivotal role in Alzheimer's disease (AD)
pathogenesis, but its normal physiological functions are less clear. Combined deletion of the …

Understanding the biological function of amyloid beta (Aβ) precursor protein (APP) beyond
its role in Alzheimer's disease is emerging. Yet, its function during embryonic development is …

The human amyloid protein precursor (APP) gene correlates with early onset of Alzheimer's
disease in humans. We have identified two APP homologues in zebrafish, which we call …

Interest in the amyloid precursor protein (APP) has increased in recent years due to its
involvement in Alzheimer's disease. Since its molecular cloning, significant genetic and …

Lateral inhibition provides a mechanism to regulate neuroblast specification during early
neurogenesis in Drososphila melanogaster embryos. This mechanism is mediated by the …

Although abnormal processing of β-amyloid precursor protein (APP) has been implicated in
the pathogenic cascade leading to Alzheimer's disease, the normal function of this protein is …

The amyloid-β precursor protein (APP) is a transmembrane protein that is widely expressed
within the central nervous system (CNS). While the pathogenic dysfunction of this protein …