Interactions of isolated C-terminal fragments of neural Wiskott-Aldrich syndrome protein (N-WASP) with actin and Arp2/3 complex
JF Gaucher, C Maugé, D Didry, B Guichard… - Journal of Biological …, 2012 - ASBMB
Wiskott-Aldrich syndrome proteins (WASP) are a family of proteins that all catalyze actin
filament branching with the Arp2/3 complex in a variety of actin-based motile processes. The …
filament branching with the Arp2/3 complex in a variety of actin-based motile processes. The …
Identification of another actin-related protein (Arp) 2/3 complex binding site in neural Wiskott-Aldrich syndrome protein (N-WASP) that complements actin …
Neural Wiskott-Aldrich syndrome protein (N-WASP) is an essential regulator of actin
cytoskeleton formation via its association with the actin-related protein (Arp) 2/3 complex. It …
cytoskeleton formation via its association with the actin-related protein (Arp) 2/3 complex. It …
Enhancement of branching efficiency by the actin filament-binding activity of N-WASP/WAVE2
The actin-related protein (Arp) 2/3 complex is an essential regulator of de novo actin filament
formation. Arp2/3 nucleates the polymerization of actin and creates branched actin filaments …
formation. Arp2/3 nucleates the polymerization of actin and creates branched actin filaments …
Phosphorylation of the WASP-VCA domain increases its affinity for the Arp2/3 complex and enhances actin polymerization by WASP
GOC Cory, R Cramer, L Blanchoin, AJ Ridley - Molecular cell, 2003 - cell.com
Wiskott-Aldrich syndrome protein (WASP) and neural (N)-WASP regulate dynamic actin
structures through the ability of their VCA domains to bind to and stimulate the actin …
structures through the ability of their VCA domains to bind to and stimulate the actin …
Actin-bound structures of Wiskott–Aldrich syndrome protein (WASP)-homology domain 2 and the implications for filament assembly
D Chereau, F Kerff, P Graceffa… - Proceedings of the …, 2005 - National Acad Sciences
Wiskott–Aldrich syndrome protein (WASP)-homology domain 2 (WH2) is a small and
widespread actin-binding motif. In the WASP family, WH2 plays a role in filament nucleation …
widespread actin-binding motif. In the WASP family, WH2 plays a role in filament nucleation …
The verprolin-like central (vc) region of Wiskott-Aldrich syndrome protein induces Arp2/3 complex-dependent actin nucleation
K Hufner, HN Higgs, TD Pollard, C Jacobi… - Journal of Biological …, 2001 - ASBMB
Wiskott-Aldrich Syndrome protein (WASp) and related proteins stimulate actin filament
nucleation by Arp2/3 complex. The isolated C-terminal VCA domain of WASp …
nucleation by Arp2/3 complex. The isolated C-terminal VCA domain of WASp …
Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate
R Rohatgi, HH Ho, MW Kirschner - The Journal of cell biology, 2000 - rupress.org
Neuronal Wiskott-Aldrich Syndrome protein (N-WASP) transmits signals from Cdc42 to the
nucleation of actin filaments by Arp2/3 complex. Although full-length N-WASP is a weak …
nucleation of actin filaments by Arp2/3 complex. Although full-length N-WASP is a weak …
Arp2/3 complex is bound and activated by two WASP proteins
SB Padrick, LK Doolittle… - Proceedings of the …, 2011 - National Acad Sciences
Actin related protein 2/actin related protein 3 (Arp2/3) complex nucleates new actin filaments
in eukaryotic cells in response to signals from proteins in the Wiskott–Aldrich syndrome …
in eukaryotic cells in response to signals from proteins in the Wiskott–Aldrich syndrome …
Nck and phosphatidylinositol 4, 5-bisphosphate synergistically activate actin polymerization through the N-WASP-Arp2/3 pathway
R Rohatgi, P Nollau, HYH Ho, MW Kirschner… - Journal of Biological …, 2001 - ASBMB
The Wiskott-Aldrich syndrome protein (WASP) and its relative neural WASP (N-WASP)
regulate the nucleation of actin filaments through their interaction with the Arp2/3 complex …
regulate the nucleation of actin filaments through their interaction with the Arp2/3 complex …
CR16 forms a complex with N-WASP in brain and is a novel member of a conserved proline-rich actin-binding protein family
HYH Ho, R Rohatgi, L Ma… - Proceedings of the …, 2001 - National Acad Sciences
The Neuronal Wiskott–Aldrich syndrome protein (N-WASP) has emerged as a central
regulator of the actin cytoskeleton with abilities to integrate multiple upstream signal inputs …
regulator of the actin cytoskeleton with abilities to integrate multiple upstream signal inputs …