Immunomodulatory effect of curcumin on hepatic cirrhosis in experimental rats

MA Abo‐Zaid, ES Shaheen… - Journal of food …, 2020 - Wiley Online Library
Cirrhosis is a chronic liver disease. The present work aimed to evaluate the regulatory
immune effect of curcumin in hepatic cirrhosis induced by carbon tetrachloride (CCl4) …

[PDF][PDF] Antioxidant and anti-inflammatory effects of curcumin on CCl4–induced liver fibrosis in rats

NF Khedr, EG Khedr - Am. J. Biomed. Sci, 2014 - nwpii.com
Background: Liver fibrogenesis can lead to the development of cirrhosis and hepatocellular
carcinoma. This study was designed to evaluate the hepatoprotective effect of curcumin on …

Pharmacological actions of curcumin in liver diseases or damage

Y Rivera‐Espinoza, P Muriel - Liver International, 2009 - Wiley Online Library
Since 1900 bc, several therapeutic activities have been attributed to the rhizomes of the
plant Curcuma longa for a variety of diseases, including liver disorders. Curcumin, the main …

Curcumin prevents liver fibrosis by inducing apoptosis and suppressing activation of hepatic stellate cells

JC Shu, YJ He, X Lv, GR Ye, LX Wang - Journal of natural medicines, 2009 - Springer
This study was designed to investigate the prophylactic effects and the mechanisms of
curcumin on liver fibrosis in rats. Liver fibrosis was induced in 72 Sprague Dawley rats by …

Hepatoprotective properties of curcumin

K Reyes-Gordillo, R Shah, MR Lakshman… - Liver …, 2017 - Elsevier
Curcumin, a bioflavonoid obtained from the Curcuma longa plant, possesses several
beneficial properties against liver inflammation, cancer, fibrosis, viral infection, heavy metal …

Curcumin protects against acute liver damage in the rat by inhibiting NF-κB, proinflammatory cytokines production and oxidative stress

K Reyes-Gordillo, J Segovia, M Shibayama… - … et Biophysica Acta (BBA …, 2007 - Elsevier
Curcumin, an anti-inflammatory and antioxidant compound, was evaluated for its ability to
suppress acute carbon tetrachloride-induced liver damage. Acute hepatotoxicity was …

Protective effects of curcumin against hepatic fibrosis induced by carbon tetrachloride: modulation of high-mobility group box 1, Toll-like receptor 4 and 2 expression

C Tu, Q Yao, B Xu, J Wang, C Zhou, S Zhang - Food and chemical …, 2012 - Elsevier
The aim of the study was to investigate the effect of curcumin on the liver fibrosis induced by
carbon tetrachloride (CCl4) in rats, and to elucidate its underlying molecular mechanisms …

Protective effect of curcumin on the liver of high fat diet-fed rats

AA Mahmoud, A Abdelrahman, HO Abd el Aziz - Gene Reports, 2018 - Elsevier
Curcumin has been proved to have antioxidant and antiinflammatory actions. We
investigated the prophylactic effect of curcumin against the development of non-alcoholic …

Curcumin prevents and reverses cirrhosis induced by bile duct obstruction or CCl4 in rats: role of TGF‐β modulation and oxidative stress

K Reyes‐Gordillo, J Segovia… - Fundamental & …, 2008 - Wiley Online Library
Curcumin is a phytophenolic compound, which is highly efficacious for treating several
inflammatory diseases. The aim of this study was to evaluate the efficacy of curcumin in …

Curcumin and liver disease: from chemistry to medicine

SF Nabavi, M Daglia, AH Moghaddam… - … Reviews in Food …, 2014 - Wiley Online Library
Curcumin, the natural yellow‐colored active principle, also called turmeric yellow, extracted
from the perennial herb Curcuma longa L., has potent biological and pharmacological …