[HTML][HTML] COVID-19 severity in obesity: leptin and inflammatory cytokine interplay in the link between high morbidity and mortality

R Maurya, P Sebastian, M Namdeo… - Frontiers in …, 2021 - frontiersin.org
Obesity is one of the foremost risk factors in coronavirus infection resulting in severe illness
and mortality as the pandemic progresses. Obesity is a well-known predisposed chronic …

[HTML][HTML] Obesity, the most common comorbidity in SARS-CoV-2: is leptin the link?

CJ Rebello, JP Kirwan, FL Greenway - International Journal of Obesity, 2020 - nature.com
Overweight and obesity are major risk factors for diabetes, cardiovascular disease, and lung
disease. These diseases are the most commonly reported health conditions that predispose …

[HTML][HTML] Susceptibility and severity of viral infections in obesity: lessons from influenza to COVID-19. Does leptin play a role?

V Guglielmi, L Colangeli, M D'Adamo… - International Journal of …, 2021 - mdpi.com
The recent pandemic Sars-CoV2 infection and studies on previous influenza epidemic have
drawn attention to the association between the obesity and infectious diseases susceptibility …

Leptin correlates with monocytes activation and severe condition in COVID-19 patients

J Wang, Y Xu, X Zhang, S Wang, Z Peng… - Journal of leukocyte …, 2021 - academic.oup.com
Excessive monocyte activation with the development of excessive or uncontrolled release of
proinflammatory cytokines often results in host tissue injury and even death in patients with …

[HTML][HTML] Obesity and COVID-19: what makes obese host so vulnerable?

S Mohammad, R Aziz, S Al Mahri, SS Malik, E Haji… - Immunity & …, 2021 - Springer
Abstract The disease (COVID-19) novel coronavirus pandemic has so far infected millions
resulting in the death of over a million people as of Oct 2020. More than 90% of those …

[HTML][HTML] Leptin levels in SARS-CoV-2 infection related respiratory failure: A cross-sectional study and a pathophysiological framework on the role of fat tissue

PHJ van der Voort, J Moser, DF Zandstra, ACM Kobold… - Heliyon, 2020 - cell.com
Obesity is a risk factor for SARS-CoV-2 infected patients to develop respiratory failure. Leptin
produced in visceral fat might play a role in the deterioration to mechanical ventilation. A …

[HTML][HTML] Obesity and COVID-19: a detrimental intersection

MA Gammone, N D'Orazio - Frontiers in Endocrinology, 2021 - frontiersin.org
Obesity has been recognized as an independent risk factor for critical illness and major
severity in subjects with coronavirus disease 2019 (COVID-19). The role of fat distribution …

[HTML][HTML] Obesity and its impact on COVID-19

AJM de Leeuw, MAM Oude Luttikhuis… - Journal of Molecular …, 2021 - Springer
The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pandemic has proven
a challenge to healthcare systems since its first appearance in late 2019. The global spread …

[HTML][HTML] COVID-19: Is there a role for immunonutrition in obese patient?

L Di Renzo, P Gualtieri, F Pivari, L Soldati… - Journal of translational …, 2020 - Springer
On December 12, 2019 a new coronavirus (SARS-CoV-2) emerged in Wuhan, China,
triggering a pandemic of severe acute respiratory syndrome in humans (COVID-19). Today …

Obesity and COVID-19: immune and metabolic derangement as a possible link to adverse clinical outcomes

E Korakas, I Ikonomidis… - American Journal …, 2020 - journals.physiology.org
Recent reports have shown a strong association between obesity and the severity of COVID-
19 infection, even in the absence of other comorbidities. After infecting the host cells, severe …