Melatonin has been well documented for its neuroprotective role through inhibiting oxidative
stress against traumatic brain injury (TBI). However, the specific role of melatonin and the …

Traumatic brain injury (TBI) is a leading cause of long-term disability and mortality in young
adults. The devastating effects of TBI on emotion regulation, executive functioning, and …

This review covers the preclinical and clinical literature supporting the role of melatonin in
the management of brain injury-induced oxidative stress, neuroinflammation, and …

Traumatic brain injury (TBI) is followed by massive production of reactive oxygen species
(ROS), which mediate secondary cellular damage. Low molecular weight antioxidants …

Subarachnoid hemorrhage (SAH) is a common cerebrovascular disease with high mortality
and disability rates. Despite progressive advances in drugs and surgical techniques …

Traumatic brain injury (TBI) is a principal cause of death and disability worldwide. Melatonin,
a hormone made by the pineal gland, is known to have anti-inflammatory and antioxidant …

In addition to significant antioxidant properties, melatonin exhibits neuroprotective effects
against various neurological diseases including traumatic brain injury (TBI) and ischemic …

Cerebral ischemia-reperfusion (CIR) injury is initiated by the generation of reactive oxygen
species (ROS), which leads to the oxidation of cellular proteins, DNA, and lipids as an initial …

Chronic cerebral hypoperfusion (CCH) is the most common cause of cognitive impairment,
which is commonly found in Alzheimer's disease (AD) and vascular dementia (VaD) …

Melatonin (Mel) has neuroprotective effects; however, its roles in hypoxic-ischemic brain
damage (HIBD) and the underlying mechanisms remain unknown. We aimed to explore its …