Thy-1 is a membrane glycoprotein suggested to stabilize or inhibit growth of neuronal
processes. However, its precise function has remained obscure, because its endogenous …

Thy-1 is an abundant neuronal glycoprotein of poorly defined function. We recently provided
evidence indicating that Thy-1 clusters a β3-containing integrin in astrocytes to induce …

Thy-1 is an abundant neuronal glycoprotein in mammals. Despite such prevalence, Thy-1
function remains largely obscure in the absence of a defined ligand. Recently described …

Two key proteins for cellular communication between astrocytes and neurons are αvβ3
integrin and the receptor Thy-1. Binding of these molecules in the same (cis) or on adjacent …

Background: Thy-1 is an abundant neuronal glycoprotein in mammals. Despite such
prevalence, Thy-1 function remains largely obscure in the absence of a defined ligand …

Cell adhesion to the extracellular matrix proteins occurs through interactions with integrins
that bind to Arg-Gly-Asp (RGD) tripeptides, and syndecan-4, which recognizes the heparin …

Clustering of αvβ3 integrin after interaction with the RGD-like integrin-binding sequence
present in neuronal Thy-1 triggers formation of focal adhesions and stress fibers in …

Abstract Thy-1, or CD90, is a glycosylphosphatidylinositol-linked cell surface glycoprotein
expressed on multiple cell types, including neurons, thymocytes, fibroblasts, endothelial …

A recent study by Hermosilla et al.[T. Hermosilla, D. Munoz, R. Herrera-Molina, A. Valdivia,
N. Munoz, SU Nham, P. Schneider, K. Burridge, AF Quest, L. Leyton, Direct Thy …

Thy-1, a cell adhesion molecule abundantly expressed in mammalian neurons, binds to a β
3-containing integrin on astrocytes and thereby stimulates the assembly of focal adhesions …