Ischemic stroke is a debilitating disease and one of the leading causes of long-term
disability. During the early phase after ischemic stroke, the blood-brain barrier (BBB) exhibits …

Stroke is the leading cause of physical disability among adults. Stem cells such as
mesenchymal stem cells (MSCs) secrete a variety of bioactive substances, including trophic …

Background and Purpose—Recent work from our group suggests that human neural stem
cell–derived extracellular vesicle (NSC EV) treatment improves both tissue and …

Stroke is a leading cause of mortality and long-term disability globally, with acute ischemic
stroke (AIS) being the most common subtype. Despite significant advances in reperfusion …

To the editor, Ischemic stroke (IS) is one of the leading causes of mortality and disability
worldwide. 1 Among various therapeutic strategies for IS, the application/administration of …

Despite recent advances in stroke therapy, current therapeutic concepts are still limited.
Thus, additional therapeutic strategies are in order. In this sense, the transplantation of stem …

Although the initial concepts of stem cell therapy aimed at replacing lost tissue, more recent
evidence has suggested that stem and progenitor cells alike promote postischemic …

Stem cell-based treatments have been suggested as promising candidates for stroke.
Recently, mesenchymal stem cells (MSCs) have been reported as potential therapeutics for …

Following the implementation of thrombolysis and endovascular recanalization strategies,
stroke therapy has profoundly changed in recent years. In spite of these advancements, a …

Intracerebral hemorrhage following blood–brain barrier (BBB) disruption resulting from
thrombolysis of ischemic stroke with tissue plasminogen activator (tPA) remains a critical …